721457-68-7

Basic information

• Product Name: 1-(2-Bromonaphthalen-1-yl)naphthalen-2-ol
• Synonyms: 1-(2-Bromonaphthalen-1-yl)naphthalen-2-ol;2'-Bromo-1,1'-binaphthalen-2-ol
• CAS NO: 721457-68-7
• Molecular Formula: C₂₀H₁₃BrO
• Molecular Weight: 349.22062
• Mol File: 721457-68-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 462.6 °C at 760 mmHg
• Flash Point: 233.6 °C
• Appearance: /
• Density: 1.47 g/cm³
• CAS DataBase Reference: 1-(2-Bromonaphthalen-1-yl)naphthalen-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Bromonaphthalen-1-yl)naphthalen-2-ol(721457-68-7)
• EPA Substance Registry System: 1-(2-Bromonaphthalen-1-yl)naphthalen-2-ol(721457-68-7)

Safety Data

• Hazardous Substances Data: 721457-68-7(Hazardous Substances Data)

Usage

General Description

1-(2-Bromonaphthalen-1-yl)naphthalen-2-ol is a chemical compound with the molecular formula C20H13BrO. It consists of a naphthalene ring with a bromine-substituted naphthalene group attached to it, along with a hydroxyl group. 1-(2-Bromonaphthalen-1-yl)naphthalen-2-ol is used in organic synthesis and chemical research as a building block for creating new molecules with specific properties. It can also be used as a reagent in various chemical reactions due to its unique structure and reactivity. Additionally, it may have potential applications in fields such as pharmaceuticals and materials science, where its properties could be utilized for specific purposes.

Upstream product

• 602-09-5 1,1'-bi-2-naphthol 

Downstream Products

• 194-63-8 dinaphtho[2,1-b;1',2'-d]furan 

Relevant articles and documents

Sulfoxides as 'traceless' resolving agents for the synthesis of atropisomers by dynamic or classical resolution

Reacting (-)-menthyl sulfinate with an atropisomeric but racemic aryllithium gives two atropdiastereoisomeric sulfoxides. Separation (by chromatography or crystallisation) and sulfoxide-lithium exchange of each diastereoisomer regenerates the aryllithium in enantiomerically pure form which can be quenched with a range of electrophiles with retention of stereochemical integrity. Overall the reaction sequence is a resolution but without the need for an acidic or basic substituent - a 'traceless' method. In certain instances, for example when the nucleophile is an ortholithiated peri-substituted 1-naphthamide, the diastereoisomeric sulfoxides may be interconverted thermally. This allows a dynamic resolution, under thermodynamic control, and hence in principle can give yields of the final products of greater than 50%. The utility of the method is demonstrated by the synthesis of a known atropisomeric phosphine ligand.