72180-24-6 Usage
General Description
(2S,4R)-1-benzyl-2-methyl-4-fluoropyrrolidine-1,2-dicarboxy is a chemical compound with a molecular formula C16H19NO4F. It is a pyrrolidine derivative with a benzyl and a methyl group attached to the nitrogen and carbon atoms, respectively. The compound also contains a fluorine atom and two carboxylic acid groups. This chemical may have potential applications in the pharmaceutical industry due to its unique structure and properties. Its specific uses and effects on biological systems would need to be further explored through research and testing.
Check Digit Verification of cas no
The CAS Registry Mumber 72180-24-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,1,8 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 72180-24:
(7*7)+(6*2)+(5*1)+(4*8)+(3*0)+(2*2)+(1*4)=106
106 % 10 = 6
So 72180-24-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H16FNO4/c1-14(12(17)18)7-11(15)8-16(14)13(19)20-9-10-5-3-2-4-6-10/h2-6,11H,7-9H2,1H3,(H,17,18)/t11-,14?/m1/s1
72180-24-6Relevant articles and documents
Synthesis and Pharmacological Activity of Angiotensin Converting Enzyme Inhibitors: N-(Mercaptoacyl)-4-substituted-(S)-prolines
Smith, Elisabeth M.,Swiss, Gerald F.,Neustadt, Bernard R.,Gold, Elijah H.,Sommer, Jane A.,et al.
, p. 875 - 885 (2007/10/02)
The synthesis of a series of N-(mercaptoacyl)-4-substituted-(S)-prolines (2 and 3) is described.These compounds were evaluated in vitro for inhibition of angiotensin-converting enzyme (ACE), and selected compounds were evaluated in vivo for ACE inhibition.The most potent compounds in vitro are 108, 109, 111, 114, and 116, having relative potencies of 1.0, 1.0, 1.3, 1.1, and 2.6 as compared to the potency of captopril.The most potent compounds in vivo intravenously are 108, 111, 114, 116, 117, and 97.
