72180-34-8

Basic information

• Product Name: (S)-5-Hydroxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester
• CAS NO: 72180-34-8
• Molecular Weight: 293.32
• Mol File: 72180-34-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-5-Hydroxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-Hydroxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester(72180-34-8)
• EPA Substance Registry System: (S)-5-Hydroxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester(72180-34-8)

Safety Data

• Hazardous Substances Data: 72180-34-8(Hazardous Substances Data)

Upstream product

• 65427-31-8 (S)-2-Benzyloxycarbonylamino-6-chloro-5-oxo-hexanoic acid methyl ester 
• 15366-19-5 methyl (S)-2-benzyloxycarbonylamino-6-diazo-5-oxohexanoate 
• 5672-83-3 Z-L-GluOMe 
• 23632-67-9 (S)-3-[3-(benzyloxycarbonyl)-5-oxooxazolidin-4-yl]propanoic acid 
• 117836-15-4 (S)-2-Benzyloxycarbonylamino-5-ethoxycarbonyloxy-5-oxo-pentanoic acid methyl ester 
• 117836-20-1 (S)-2-Benzyloxycarbonylamino-5-(tert-butyl-dimethyl-silanyloxy)-6-chloro-hexanoic acid methyl ester 
• 117836-18-7 (S)-2-Benzyloxycarbonylamino-6-chloro-5-trimethylsilanyloxy-hexanoic acid methyl ester 
• 117836-16-5 (S)-2-Benzyloxycarbonylamino-6-chloro-5-hydroxy-hexanoic acid methyl ester 
• 1155-62-0 N-benzyloxycarbonyl-L-glutamic acid 
• 117836-22-3 (S)-5-Trimethylsilanyloxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 117836-24-5 (S)-5-(tert-Butyl-dimethyl-silanyloxy)-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 

Downstream Products

• 63088-78-8 (2S,5R)-5-hydroxypiperidine-2-carboxylic acid 
• 917507-80-3 (2S,5S)-N-[(benzyloxy)carbonyl]-5-hydroxy-2-piperidinecarboxylic acid 
• 117836-26-7 cis-5(S)-hydroxy-2(S)-N₁-benzyloxycarbonylpipecolic acid methyl ester 
• 107476-23-3 3-Oxo-2-oxa-5-aza-bicyclo[2.2.2]octane-5-carboxylic acid benzyl ester 
• 117836-27-8 (2S,5R)-5-Hydroxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 

Relevant articles and documents

CHIRAL SYNTHESIS OF 5-HYDROXY-(L)-PIPECOLIC ACIDS FROM (L)-GLUTAMIC ACID

A stereo- and enantio-specific synthesis of the naturally occuring cis-5-hydroxy-(L)-pipecolic acid (3) is described, starting from Z-(L)-glutamic acid; the key step involves cyclisation of a protected chlorohydrin, and also gives access to trans-5-hydroxy-(L)-pipecolic acid.