72235-57-5 Usage
General Description
4-Chloro-2-fluorobenzyl amine is a chemical compound with the molecular formula C7H6ClFN and it is also known by its IUPAC name, 4-Chloro-2-fluorobenzenemethanamine. It belongs to the class of organic compounds known as benzene and its substituted derivatives, which are aromatic compounds containing one monocyclic ring system made of benzene. This particular compound has chlorine and fluorine substituents on the benzene ring. The chemical has applications in various areas of chemistry, particularly in the synthesis of more complex chemical compounds. Its characteristics, such as reactivity and toxicity, are determined by its precise molecular structure.
Check Digit Verification of cas no
The CAS Registry Mumber 72235-57-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,2,3 and 5 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 72235-57:
(7*7)+(6*2)+(5*2)+(4*3)+(3*5)+(2*5)+(1*7)=115
115 % 10 = 5
So 72235-57-5 is a valid CAS Registry Number.
72235-57-5Relevant articles and documents
Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity
Leonard, Kristi,Marugan, Juan Jose,Raboisson, Pierre,Calvo, Raul,Gushue, Joan M.,Koblish, Holly K.,Lattanze, Jennifer,Zhao, Shuyuan,Cummings, Maxwell D.,Player, Mark R.,Maroney, Anna C.,Lu, Tianbao
, p. 3463 - 3468 (2007/10/03)
The disruption of the p53-Hdm2 protein-protein interaction induces cell growth arrest and apoptosis. We have identified the 1,4-benzodiazepine-2,5-dione scaffold as a suitable template for inhibiting this interaction by binding to the Hdm2 protein. Several compounds have been made with improved potency, solubility, and cell-based activities.
