725235-72-3

Basic information

• Product Name: tert-butyl (4-{[8-carbamoyl-7-(3,5-dimethoxyphenylamino)imidazo[1,2-c]pyrimidin-5-ylamino]methyl}phenyl)acetate
• Synonyms: tert-butyl (4-{[8-carbamoyl-7-(3,5-dimethoxyphenylamino)imidazo[1,2-c]pyrimidin-5-ylamino]methyl}phenyl)acetate
• CAS NO: 725235-72-3
• Molecular Weight: 532.599
• Mol File: 725235-72-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (4-{[8-carbamoyl-7-(3,5-dimethoxyphenylamino)imidazo[1,2-c]pyrimidin-5-ylamino]methyl}phenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (4-{[8-carbamoyl-7-(3,5-dimethoxyphenylamino)imidazo[1,2-c]pyrimidin-5-ylamino]methyl}phenyl)acetate(725235-72-3)
• EPA Substance Registry System: tert-butyl (4-{[8-carbamoyl-7-(3,5-dimethoxyphenylamino)imidazo[1,2-c]pyrimidin-5-ylamino]methyl}phenyl)acetate(725235-72-3)

Safety Data

• Hazardous Substances Data: 725235-72-3(Hazardous Substances Data)

Upstream product

• 725234-60-6 7-(3,5-dimethoxy-phenylamino)-5-methylsulfanyl-imidazo[1,2-c]pyrimidine-8-carboxylic acid amide 
• 479586-24-8 tert-butyl [4-(aminomethyl)phenyl]acetate 

Downstream Products

• 725235-74-5 (4-{[8-carbamoyl-7-(3,5-dimethoxyphenylamino)imidazo[1,2-c]pyrimidin-5-ylamino]methyl}phenyl)acetic acid 

Relevant articles and documents

Structure-activity relationship studies of 5-benzylaminoimidazo[1,2-c]pyrimidine-8-carboxamide derivatives as potent, highly selective ZAP-70 kinase inhibitors

Zeta-associated protein, 70 kDa (ZAP-70), a spleen tyrosine kinase (Syk) family kinase, is normally expressed on T cells and natural killer cells and plays a crucial role in activation of the T cell immunoresponse. Thus, selective ZAP-70 inhibitors might