7260-07-3

Basic information

• Product Name: butyl 3-hydroxynaphthalene-2-carboxylate
• CAS NO: 7260-07-3
• Molecular Formula: C₁₅H₁₆O₃
• Molecular Weight: 244.2857
• Mol File: 7260-07-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 370.4°C at 760 mmHg
• Flash Point: 153.3°C
• Density: 1.166g/cm³
• Vapor Pressure: 5.22E-06mmHg at 25°C
• Refractive Index: 1.6
• CAS DataBase Reference: butyl 3-hydroxynaphthalene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: butyl 3-hydroxynaphthalene-2-carboxylate(7260-07-3)
• EPA Substance Registry System: butyl 3-hydroxynaphthalene-2-carboxylate(7260-07-3)

Safety Data

• Hazardous Substances Data: 7260-07-3(Hazardous Substances Data)

Upstream product

• 92-70-6 3-Hydroxy-2-naphthoic acid 
• 71-36-3 butan-1-ol 
• 876891-35-9 (1H-benzo[d][1,2,3]triazol-1-yl)(3-hydroxynaphthalen-2-yl)methanone 

Downstream Products

• 145372-03-8 Butyl 2,2'-dihydroxy-1,1'-binaphthalene-3-carboxylate 
• 145372-04-9 2,2'-Dihydroxy-[1,1']binaphthalenyl-3,3'-dicarboxylic acid dibutyl ester 
• 602-09-5 1,1'-bi-2-naphthol 

Relevant articles and documents

Zn(OTf)2-promoted chemoselective esterification of hydroxyl group bearing carboxylic acids

Selective esterification of aliphatic and aromatic carboxylic acids with various alcohols is studied using triphenylphosphine, I2, and a catalytic amount of Zn(OTf)2. Use of this catalyst allows the formation of esters at a faster rate with good to excellent yield by activating the in situ generated acyloxyphosphonium ion intermediate. During the esterification process, both their aromatic and aliphatic hydroxyl groups are fully preserved from transesterification. The results show that the bulkiness and the reactivity of this doubly activated intermediate III control the selectivity and the rate of the reaction, respectively. The method is also useful for direct amidation reactions.

The oxidative cross-coupling of substituted 2-naphthols. Part I: The scope and limitations

Highly selective oxidative cross-coupling of differently substituted 2-naphthols mediated by Cu(II)-tert-butyl amine complexes is described. The 'cross'-products are obtained in good to excellent yields and the selectivity up to >90% is observed depending on the substitution of naphthol nuclei. The alternative procedures - the cross-coupling of free naphthols with CuCl(OMe) as well as the coupling of sodium naphtholates with anhydrous copper(II) chloride - were also studied. All these methods enable a simple and high-yield access to the unsymmetrically substituted binaphthols. A successful optical resolution of methyl 2,2'-dihydroxy-1,1'-binaphthalene-3-carboxylate by means of liquid chromatography on triacetylcellulose and the subsequent configurational correlation with a binaphthol derivative of known absolute configuration is reported.