72754-05-3 Usage
Uses
6-Bromo-1,8-naphthyridin-2(1H)-one is used as an organic chemical synthesis intermediate.
Check Digit Verification of cas no
The CAS Registry Mumber 72754-05-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,7,5 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 72754-05:
(7*7)+(6*2)+(5*7)+(4*5)+(3*4)+(2*0)+(1*5)=133
133 % 10 = 3
So 72754-05-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrN2O/c9-6-3-5-1-2-7(12)11-8(5)10-4-6/h1-4H,(H,10,11,12)
72754-05-3Relevant articles and documents
1H-1,8- NAPHTHYRIDIN-2ONES AS ANTI PROLIFERATIVE COMPOUNDS
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, (2015/12/30)
The present invention relates to novel antiproliferative1H-1, 8-naphthyridin-2-ones of the general formula (I) or pharmaceutically acceptable salts thereof: In which the variable groups are as defined herein, and their preparation and use in therapeutic treatment of disorders related to inhibition of tyrosine kinases in warm blooded animals. The compounds can overcome imatinib induced drug resistance.
