72835-86-0

Basic information

• Product Name: 3-(3,4-DIMETHYL-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
• Synonyms: ETHYL (3,4-DIMETHYLBENZOYL)ACETATE;3-(3,4-DIMETHYL-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER;3,4-DIMETHYL-BETA-OXO-BENZENEPROPANOIC ACID ETHYL ESTER
• CAS NO: 72835-86-0
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.26
• Mol File: 72835-86-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(3,4-DIMETHYL-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-DIMETHYL-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER(72835-86-0)
• EPA Substance Registry System: 3-(3,4-DIMETHYL-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER(72835-86-0)

Safety Data

• Hazardous Substances Data: 72835-86-0(Hazardous Substances Data)

Upstream product

• 3637-01-2 3,4-dimethylacetophenone 
• 105-58-8 Diethyl carbonate 

Downstream Products

• 107846-97-9 2-(3,4-Dimethyl-phenyl)-3-isobutyryl-indolizine-1-carboxylic acid ethyl ester 
• 107846-93-5 3-Acetyl-2-(3,4-dimethyl-phenyl)-indolizine-1-carboxylic acid ethyl ester 

Relevant articles and documents

Trifluoroethanol as a Unique Additive for the Chemoselective Electrooxidation of Enamines to Access Unsymmetrically Substituted NH-Pyrroles

An electrochemical method for the synthesis of unsymmetrically substituted NH-pyrroles is described. The synthetic strategy comprises a challenging heterocoupling between two structurally diverse enamines via sequential chemoselective oxidation, addition,

Construction of isoxazolone-fused phenanthridinesviaRh-catalyzed cascade C-H activation/cyclization of 3-arylisoxazolones with cyclic 2-diazo-1,3-diketones

A Rh(iii)-catalyzed cascade C-H activation/intramolecular cyclization of 3-aryl-5-isoxazolones with cyclic 2-diazo-1,3-diketones was described, leading to the formation of isoxazolo[2,3-f]phenanthridine skeletons. The protocol features the simultaneous one-pot formation of two new C-C/C-N bonds and one heterocycle in moderate-to-good yields with good functional group compatibility. It is amenable to large-scale synthesis and further transformation.

Desymmetrization of meso-dicarbonatecyclohexene with β-Hydrazino carboxylic esters via a Pd-catalyzed allylic substitution cascade

The desymmetrization of meso-dicarbonatecyclohexene with β-hydrazino carboxylic esters has been achieved via a RuPHOX/Pd-catalyzed allylic substitution cascade for the construction of chiral hexahydrocinnoline derivatives with high performance. Mechanistic studies reveal that the reaction exploits a pathway different from that of our previous work and that the first nitrogen nucleophilic process is the rate-determining step. The protocol could be conducted on a gram scale without any loss of catalytic behavior, and the corresponding chiral hexahydrocinnolines can undergo diverse transformations.