73-49-4

Basic information

• Product Name: QUINETHAZONE (1.5 G)
• Synonyms: 2-Ethyl-7-chloro-6-sulfamoyl-1,2-dihydroquinazoline-4(3H)-one;7-Chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-quinazolinesulfonamide;7-chloro-2-ethyl-4-keto-2,3-dihydro-1H-quinazoline-6-sulfonamide;7-chloro-2-ethyl-4-oxo-2,3-dihydro-1H-quinazoline-6-sulfonamide;2-Ethyl-7-chloro-1,2,3,4-tetrahydro-4-oxoquinazoline-6-sulfonaMide;2-Ethyl-7-chloro-2,3-dihydro-4(1H)-quinazolone-6-sulfonaMide;7-Chloro-2-ethyl-6-sulfaMyl-1,2,3,4-tetrahydro-4-quinazolinone;QuinethazonuM
• CAS NO: 73-49-4
• Molecular Formula: C₁₀H₁₂ClN₃O₃S
• Molecular Weight: 289.73858
• EINECS: 200-801-7
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
• Mol File: 73-49-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 250-252°
• Appearance: white powder
• Density: 1.4208 (rough estimate)
• Refractive Index: 1.6300 (estimate)
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
• PKA: pKa 9.3 (Uncertain);10.7 (Uncertain)
• Water Solubility: 0.15g/L(25 oC)
• Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
• CAS DataBase Reference: QUINETHAZONE (1.5 G)(CAS DataBase Reference)
• NIST Chemistry Reference: QUINETHAZONE (1.5 G)(73-49-4)
• EPA Substance Registry System: QUINETHAZONE (1.5 G)(73-49-4)

Safety Data

• Hazardous Substances Data: 73-49-4(Hazardous Substances Data)

Usage

Chemical Properties

white powder

Uses

Quinethazone is a thiazide diuretic used to treat hypertension.

Brand name

Hydromox (Lederle).

General Description

Fibrous crystals or white powder.

Air & Water Reactions

Insoluble in water.

Fire Hazard

Flash point data for QUINETHAZONE (1.5 G) are not available; however, QUINETHAZONE (1.5 G) is probably combustible.

InChI:InChI=1/C10H12ClN3O3S/c1-2-9-13-7-4-6(11)8(18(12,16)17)3-5(7)10(15)14-9/h3-4,9,13H,2H2,1H3,(H,14,15)(H2,12,16,17)