73096-42-1

Basic information

• Product Name: 5-(2-BROMOPHENYL)-1H-TETRAZOLE
• Synonyms: LABOTEST-BB LT00441147;5-(2-BROMOPHENYL)-1H-TETRAZOLE;5-(2-BROMOPHENYL)TETRAZOLE;5-(2-Bromophenyl)tetrazole, 98+%;2-BPT;5-(2-BROMOPHENYL)-1H-TETRAZOLE,98.0+%(LC)(T);5-(2-Bromophenyl)-1H-tetrazole, 98+%;5-(2-Bromophenyl)-1H-tetrazole,99%
• CAS NO: 73096-42-1
• Molecular Formula: C₇H₅BrN₄
• Molecular Weight: 225.05
• Product Categories: TetrazolesHeterocyclic Building Blocks;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Tetrazoles
• Mol File: 73096-42-1.mol
• Article Data: 36

Chemical Properties

• Melting Point: 182-184 °C(lit.)
• Boiling Point: 389.3 °C at 760 mmHg
• Flash Point: 189.2 °C
• Appearance: /
• Density: 1.8047 (rough estimate)
• Vapor Pressure: 2.88E-06mmHg at 25°C
• Refractive Index: 1.6700 (estimate)
• Storage Temp.: Flammables area
• PKA: 3.78±0.10(Predicted)
• BRN: 148567
• CAS DataBase Reference: 5-(2-BROMOPHENYL)-1H-TETRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-BROMOPHENYL)-1H-TETRAZOLE(73096-42-1)
• EPA Substance Registry System: 5-(2-BROMOPHENYL)-1H-TETRAZOLE(73096-42-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37
• WGK Germany: 3
• Hazardous Substances Data: 73096-42-1(Hazardous Substances Data)

Usage

Chemical Properties

white to off-white powder

General Description

5-(2-Bromophenyl)-1H-tetrazole is a 5-substituted 1H-tetrazole. It can be synthesized via silica supported sulfuric acid catalyzed [3+2] cycloaddition of nitriles and sodium azide. Copper-catalyzed reaction of 5-(2-bromophenyl)-1H-tetrazole with ethyl 2-cyanoacetate has been reported to afford ethyl 1,3-diaminoisoquinoline-4-carboxylate.

InChI:InChI=1/C7H4BrN4/c8-6-4-2-1-3-5(6)7-9-11-12-10-7/h1-4H/q-1

Upstream product

• 624-84-0 formic acid hydrazide 
• 2042-37-7 o-cyanobromobenzene 
• 1461-22-9 tributyltin chloride 
• 123-91-1 1,4-dioxane 
• 4001-73-4 2-Bromobenzamide 
• 18039-42-4 5-Phenyl-1H-tetrazole 
• 6630-33-7 ortho-bromobenzaldehyde 

Downstream Products

• 143945-72-6 N-trityl-5-(2-bromophenyl)tetrazole 
• 18039-42-4 5-Phenyl-1H-tetrazole 
• 160514-13-6 5-(4'-hydroxymethyl-biphenyl-2-yl)-1H-tetrazole 
• 151052-40-3 2'-(1H-tetrazol-5-yl)biphenyl-4-carbaldehyde 
• 883223-07-2 5-(2'-bromophenyl)-2-trityl-2H-tetrazole 
• 676130-02-2 5-(2-bromophenyl)-2-(tetrahydropyran-2-yl)-2H-tetrazole 
• 676130-03-3 5-(2-bromophenyl)-1-(tetrahydropyran-2-yl)-1H-tetrazole 
• 1029083-94-0 irbesartan trifluoroacetate 
• 1029083-82-6 5-(3'-chloro-biphenyl-2-yl)-1H-tetrazole 
• 1029083-86-0 5-(4'-methoxy-biphenyl-2-yl)-1H-tetrazole 
• 1029083-89-3 5-(2'-methoxy-biphenyl-2-yl)-1H-tetrazole 
• 137862-53-4 N-pentanoyl-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]-methyl]-(L)-valine 
• 137863-20-8 (S)-N-(1-benzyloxycarbonyl-2-methyl-prop-1-yl)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amine 
• 676129-95-6 (S)-3-methyl-2-{pentanoyl-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butyric acid tert-butyl ester 

Relevant articles and documents

Synthesis and characterization of magnetic Fe3O4@Creatinine@Zr nanoparticles as novel catalyst for the synthesis of 5-substituted 1H-tetrazoles in water and the selective oxidation of sulfides with classical and ultrasonic methods

Tetrazoles and sulfoxide compounds have a wide range of applications in industries and are of great expectation to be environmentally friendly and cost-effective. This paper reports the introduction of zirconium supported on Fe3O4 na

TMSN3-Bu2Sn(OAc)2: A modified and mild reagent system for Wittenberger tetrazole-synthesis

Treatments of various nitriles with TMSN3 and Bu2Sn(OAc)2 at 30 °C in benzene for 60 h yielded the corresponding 5-substituted 1H-tetrazoles in good to excellent yields. This method is a mild and efficient alternative reagent system for Wittenberger tetrazole-synthesis that uses TMSN3 and Bu2SnO in toluene at high temperature (93–110 °C) for 24–72 h.

Humic acid as an efficient and reusable catalyst for one pot three-component green synthesis of 5-substituted 1: H -tetrazoles in water

Humic acid is a non toxic, inexpensive, easily available high-molecular weight polymer. A simple and facile one pot three-component synthesis of 5-substituted 1H-tetrazoles from aldehydes, hydroxyamine hydrochloride and sodium azide using humic acid as an efficient catalyst in water is described. The method reported has several advantages such as high to excellent yields, easy work-up, mild reaction conditions, use of water as a green solvent, and a commercially available, nontoxic and reusable catalyst.