7314-43-4

Basic information

• Product Name: AMINO-(3-METHOXY-PHENYL)-ACETIC ACID
• Synonyms: AMINO-(3-METHOXY-PHENYL)-ACETIC ACID;VITAS-BB TBB000145;2-(3-Methoxyphenyl)glycine;2-Amino-2-(3-methoxyphenyl)
• CAS NO: 7314-43-4
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 181.19
• Product Categories: pharmacetical
• Mol File: 7314-43-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 332.9 °C at 760 mmHg
• Flash Point: 155.1 °C
• Appearance: /
• Density: 1.246 g/cm³
• Vapor Pressure: 5.64E-05mmHg at 25°C
• Refractive Index: 1.568
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: AMINO-(3-METHOXY-PHENYL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: AMINO-(3-METHOXY-PHENYL)-ACETIC ACID(7314-43-4)
• EPA Substance Registry System: AMINO-(3-METHOXY-PHENYL)-ACETIC ACID(7314-43-4)

Safety Data

• Hazardous Substances Data: 7314-43-4(Hazardous Substances Data)

Usage

General Description

Amino-(3-methoxy-phenyl)-acetic acid is a chemical compound with the molecular formula C9H11NO3. It is an amino acid derivative that contains an amino group, a phenyl group, and a carboxylic acid group. The compound has potential pharmaceutical applications due to its structural similarity to natural amino acids and its ability to interact with biological systems. Amino-(3-methoxy-phenyl)-acetic acid may be used in the development of new drugs or as a precursor in organic synthesis. Its properties and potential uses make it an interesting compound for further research and development.

InChI:InChI=1/C9H11NO3/c1-13-7-4-2-3-6(5-7)8(10)9(11)12/h2-5,8H,10H2,1H3,(H,11,12)

Upstream product

• 26767-10-2 2-(3-methoxyphenyl)glyoxylic acid 
• 626-20-0 3-methoxystyrene 
• 32345-63-4 1-(3-methoxyphenyl)-1,2-ethanediol 
• 86215-57-8 bromo-(3-methoxy-phenyl)-acetic acid methyl ester 
• 591-31-1 3-methoxy-benzaldehyde 
• 271583-61-0 2-(N-benzylamino)-2-(3-methoxyphenyl)acetonitrile 
• 271583-24-5 benzylamino-(3-methoxy-phenyl)-acetic acid 
• 129592-95-6 methyl N-(trifluoroacetyl)-2-amino-2-(3-methoxyphenyl)acetate 

Downstream Products

• 125190-66-1 N-(benzyloxycarbonyl)-(R,S)-(3-methoxyphenyl)glycine 
• 848564-51-2 [3-(1-{methyl-[(4-trifluoromethyl-phenyl)-acetyl]-amino}-2-pyrrolidin-1-yl-ethyl)-phenoxy]-acetic acid tert-butyl ester 
• 261524-04-3 N-[1-(3-hydroxy-phenyl)-2-pyrrolidin-1-yl-ethyl]-N-methyl-2-(4-trifluoromethyl-phenyl)-acetamide 
• 261524-02-1 N-[1-(3-methoxy-phenyl)-2-pyrrolidin-1-yl-ethyl]-N-methyl-2-(4-trifluoromethyl-phenyl)-acetamide 
• 261524-26-9 [1-(3-methoxy-phenyl)-2-oxo-2-pyrrolidin-1-yl-ethyl]-carbamic acid methyl ester 
• 125190-67-2 [1-(3-Methoxy-phenyl)-2-pyrrolidin-1-yl-ethyl]-methyl-amine 
• 31932-87-3 D-α-amino-m-hydroxyphenylacetic acid 

Relevant articles and documents

Synthesis of Unprotected 2-Arylglycines by Transamination of Arylglyoxylic Acids with 2-(2-Chlorophenyl)glycine

The transamination of α-keto acids with 2-phenylglycine is an effective methodology for directly synthesizing unprotected α-amino acids. However, the synthesis of 2-arylglycines by transamination is problematic because the corresponding products, 2-arylglycines, transaminate the starting arylglyoxylic acids. Herein, we demonstrate the use of commercially available l-2-(2-chlorophenyl)glycine as the nitrogen source in the transamination of arylglyoxylic acids, producing the corresponding 2-arylglycines without interference from the undesired self-transamination process.

N-Alkylation of Trifluoroacetamide with 2-Bromo Carboxylic Esters under PTC conditions: A New Procedure for the Synthesis of α-Amino Acids

-