73199-40-3

Basic information

• Product Name: 7-chloro-7endo-phenyl-1-(trimethylsiloxy)bicyclo<3.2.0>heptan-6-one
• Synonyms: 7-chloro-7endo-phenyl-1-(trimethylsiloxy)bicyclo<3.2.0>heptan-6-one
• CAS NO: 73199-40-3
• Molecular Weight: 308.88
• Mol File: 73199-40-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-chloro-7endo-phenyl-1-(trimethylsiloxy)bicyclo<3.2.0>heptan-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-chloro-7endo-phenyl-1-(trimethylsiloxy)bicyclo<3.2.0>heptan-6-one(73199-40-3)
• EPA Substance Registry System: 7-chloro-7endo-phenyl-1-(trimethylsiloxy)bicyclo<3.2.0>heptan-6-one(73199-40-3)

Safety Data

• Hazardous Substances Data: 73199-40-3(Hazardous Substances Data)

Upstream product

• 2912-62-1 α-chlorophenylacetyl chloride 
• 19980-43-9 1-(trimethylsilyloxy)cyclopentene 

Downstream Products

• 73199-41-4 7-chloro-1-hydroxy-7endo-phenylbicyclo<3.2.0>heptan-6-one 

Relevant articles and documents

Synthesis of 2-substituted 1,3-cycloheptanedione via a lewis acid mediated ring expansion reaction

We have established a new route to provide 2-substituted 1,3-cycloheptanediones via a Lewis acid mediated ring expansion reaction of cyclobutanones as the key step. The ring expansion reactions were mediated by a series of Lewis acids. Among the used Lewis acids, ZnI2 was the most practical mediator. This route has succeeded in providing the title compounds even on a multi-gram scale. During the research, the Baeyer-Villiger oxidation of the cyclobutanones to obtain the new bicyclic lactones was also examined. The regioselective oxidation was observed in the case of chlorinated cyclobutanones.