73257-45-1

Basic information

• Product Name: dimethyl 4-(3-chlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
• Synonyms: dimethyl 4-(3-chlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
• CAS NO: 73257-45-1
• Molecular Formula: C₁₇H₁₈ClNO₄
• Molecular Weight: 335.78212
• Mol File: 73257-45-1.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: dimethyl 4-(3-chlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 4-(3-chlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate(73257-45-1)
• EPA Substance Registry System: dimethyl 4-(3-chlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate(73257-45-1)

Safety Data

• Hazardous Substances Data: 73257-45-1(Hazardous Substances Data)

Upstream product

• 105-45-3 acetoacetic acid methyl ester 
• 587-04-2 m-Chlorobenzaldehyde 
• 14205-39-1 methyl 3-aminocrotonate 
• 5837-80-9 methyl 2-acetoxy acetate 
• 136814-25-0 dimethyl 7-(3-chlorophenyl)-5,8a-dimethyl-2,3,7,8-tetrahydro-7H-oxazolo<3,2-a>pyridin-6,8-dicarboxylate 

Downstream Products

• 1015135-68-8 dimethyl 6-(3-chlorophenyl)-3,4-dimethyl-2,5-pyridinedicarboxylate 
• 1015135-67-7 dimethyl 2-(3-chlorophenyl)-5,6-dimethyl-3,4-pyridinedicarboxylate 
• 103026-82-0 (+/-)-dimethyl 4-(3-chlorophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate 
• 120260-22-2 8-(3-Chloro-phenyl)-3H,5H-difuro[3,4-b;3',4'-e]pyridine-1,7-dione 
• 120260-17-5 8-(3-Chloro-phenyl)-5,8-dihydro-3H,4H-difuro[3,4-b;3',4'-e]pyridine-1,7-dione 

Relevant articles and documents

Synthesis, evaluation of pharmacological activity, and molecular docking of 1,4-dihydropyridines as calcium antagonists

1,4-Dihydropyridine (DHP) is an important class of calcium antagonist. It inhibits the influx of extracellular Ca2+ through L-type voltage-dependent calcium channels. Two series of nifedipine analogues were synthesized and evaluated as calcium

Ultrasound-accelerated synthesis of 1,4-dihydropyridines in an ionic liquid

Hantzsch 1,4-dihydropyridine compounds were synthesized efficiently in high yields at room temperature within short times in 1,1,3,3-N,N,N′,N′- tetramethylguanidinium trifluoroacetate as ionic liquid using ultrasound irradiation. The ionic liquid can be recovered conveniently and reused efficiently. Springer-Verlag 2006.

Enantiospecific synthesis of dihydropyridines from chiral enamines

A new asymmetric synthesis of dihydropyridines is described. This methodology is based on the use of chiral aminoalcohols to produce enamines, which were used in the synthesis of enantiopure 2-alkyl-2,3,8,8a-tetrahydro-7H-oxazolo[3,2-a]pyridines. The known stereochemistry of these compounds was exploited to obtain 1,4-dihydropyridines with controlled configuration at C-4.