73322-71-1 Usage
Description
S-(P-AZIDOPHENACYL)GLUTATHIONE is a chemical compound that serves as an inhibitor in the field of biochemistry. It is specifically designed for the photolabeling of human and murine multidrug resistance protein 1, which is a crucial aspect in understanding and potentially overcoming drug resistance in various diseases.
Uses
Used in Biochemical Research:
S-(P-AZIDOPHENACYL)GLUTATHIONE is used as an inhibitor for photolabeling human and murine multidrug resistance protein 1. This application is essential in studying the mechanisms of drug resistance and developing strategies to combat it. By photolabeling the protein, researchers can gain insights into its structure, function, and interactions with other molecules, which can ultimately lead to the development of more effective treatments for diseases affected by drug resistance.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, S-(P-AZIDOPHENACYL)GLUTATHIONE is used as a tool to identify and characterize multidrug resistance proteins. This knowledge can be applied to the development of new drugs and therapies that can overcome resistance mechanisms, leading to more effective treatments for patients. Additionally, understanding the role of these proteins in drug resistance can help in the design of targeted drug delivery systems, ensuring that therapeutic agents reach their intended targets and minimize side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 73322-71-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,3,2 and 2 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 73322-71:
(7*7)+(6*3)+(5*3)+(4*2)+(3*2)+(2*7)+(1*1)=111
111 % 10 = 1
So 73322-71-1 is a valid CAS Registry Number.
InChI:InChI=1/C18H22N6O7S/c19-12(18(30)31)5-6-15(26)22-13(17(29)21-7-16(27)28)8-32-9-14(25)10-1-3-11(4-2-10)23-24-20/h1-4,12-13H,5-9,19H2,(H,21,29)(H,22,26)(H,27,28)(H,30,31)/t12-,13-/m0/s1
73322-71-1Relevant articles and documents
Photoaffinity Labels for Enzymes Capable of Binding Glutathione or its Disulphide
Silva, Claudius D',Seddon, Andrew P.,Douglas, Kenneth T.
, p. 3029 - 3033 (1981)
The syntheses and photolyses of several glutathione analogues incorporating aryl azide moieties on the N-terminus or SH sites are described.Such labels include S-blocked glutathiones, N,S-blocked glutathiones and an N,N'-blocked glutathione disulphide.S-(
