73325-67-4

Basic information

• Product Name: BENZYL-PYRIDIN-4-YLMETHYL-AMINE
• Synonyms: BENZYL-PYRIDIN-4-YLMETHYL-AMINE;4-PYRIDINEMETHANAMINE,N-(PHENYLMETHYL);N-Benzyl-1-(pyridin-4-yl);N-benzyl-1-(pyridin-4-yl)methanamine
• CAS NO: 73325-67-4
• Molecular Formula: C₁₃H₁₄N₂
• Molecular Weight: 198.26
• Mol File: 73325-67-4.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 330.4 °C at 760 mmHg
• Flash Point: 153.7 °C
• Appearance: /
• Density: 1.071 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: BENZYL-PYRIDIN-4-YLMETHYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL-PYRIDIN-4-YLMETHYL-AMINE(73325-67-4)
• EPA Substance Registry System: BENZYL-PYRIDIN-4-YLMETHYL-AMINE(73325-67-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 73325-67-4(Hazardous Substances Data)

Usage

General Description

Benzyl-pyridin-4-ylmethyl-amine is a chemical compound that belongs to the class of organic compounds known as benzylic amines. These are organic compounds containing an amine group attached directly to a benzene ring. Benzyl-pyridin-4-ylmethyl-amine is not commonly encountered in nature and is typically utilized in various chemical reactions as a synthetic intermediate. It may also be involved in the creation of complex molecules for a variety of industrial applications, including the development of pharmaceutical drugs and dyes. Specific details about this compound such as its physical properties, toxicity levels, and health effects largely remain to be identified.

InChI:InChI=1/C13H14N2/c14-13(12-6-8-15-9-7-12)10-11-4-2-1-3-5-11/h1-9,13H,10,14H2

Upstream product

• 3731-53-1 4-(aminomethyl)pyridine 
• 100-39-0 benzyl bromide 
• 1215021-06-9 1-benzylamino-1-(4-pyridyl)-methyl-H-phosphinic acid 
• 100-46-9 benzylamine 
• 100-52-7 benzaldehyde 
• 1037397-02-6 (Z)-1-phenyl-N-(pyridin-4-ylmethylene)methanamine oxide 
• 872-85-5 pyridine-4-carbaldehyde 
• 72954-83-7 N-<(pyridin-4-yl)methylidene>benzylamine 
• 653565-06-1 1-(N-benzylamino)-1-(4-pyridyl)methyldiphenylphosphine oxide 
• 890415-62-0 (+)-1-(N-benzylamino)-1-(4-pyridyl)-(S)-methyl-tert-butylphenyl-(S)-phosphine oxide 
• 67-56-1 methanol 
• 907594-17-6 (benzylamino-pyridin-4-yl-methyl)-methyl-phosphinic acid 
• 653565-03-8 4-pyridylmethyl(N-benzylamino)phenylphosphinic acid 
• 181178-61-0 (benzylamino-pyridin-4-yl-methyl)-phosphonic acid diphenyl ester 

Downstream Products

• 1158390-34-1 N-(2-pyridylmethyl)-benzylamine oxalate 
• 1235457-52-9 C₁₇H₁₈N₂O₃ 
• 1354698-08-0 potassium N-benzyl-N-pyridin-4-ylmethyl dithiocarbamate 
• 1384131-96-7 N-benzyl-N-(pyridin-4-ylmethyl)benzo[d]oxazol-2-amine 
• 1467079-33-9 1-benzyl-4-methyl-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one 
• 1467079-17-9 N-benzyl-N-(pyridin-4-ylmethyl)but-2-ynamide 
• 1400304-33-7 C₂₀H₂₂N₂O₄ 
• 1400304-07-5 C₁₉H₂₀N₂O₂ 
• 1400304-08-6 C₁₉H₁₈N₂O 
• 1400304-25-7 C₁₇H₁₈N₂O₂ 
• 1296885-86-3 C₃₁H₃₄ClN₇O 
• 148861-25-0 Re(C₅NH₄C₅NH₄)(CO)3(C₅NH₄CH₂NHCH₂C₆H₅)⁽¹⁺⁾*PF₆^(1-)=(Re(C₁₀N₂H₈)(CO)3(C₁₃N₂H₁₄))PF₆ 

Relevant articles and documents

Light-Triggered Nitric Oxide Release by a Photosensitizer to Combat Bacterial Biofilm Infections

Bacterial biofilms are a serious global health concern, often responsible for persistent infections. New strategies to prevent and treat bacterial infections by eradication of the biofilms are urgently needed. A novel ruthenium-based compound is reported in this study that functions as both a boronic acid-decorated photosensitizer (PS) and a light-triggered nitric oxide (NO) releasing agent. The compound can selectively attach to the bacterial membrane and biofilms and it is highly potent at eradicating Pseudomonas aeruginosa biofilms through the simultaneous release of NO and reactive oxygen species (ROS). The compound, which is more effective than clinical antibiotic tobramycin, also has excellent bacterial specificity and shows no significant cytotoxicity to human cells. The results reveal potential applications of this innovative dual-functional photoactivated ruthenium compound to combat bacterial biofilm infections.

Synthesis of α-amino acids through samarium(II) iodide promoted reductive coupling of nitrones with CO2

Several N-benzylnitrones reacted with carbon dioxide in the presence of samarium(II) iodide leading to α-amino acids as the products of reductive C-C coupling. The best selectivities were observed at a carbon dioxide pressure of 50 bar at ambient temperature. The influences of different functional groups in the nitrone backbone and of the coordinating additives to samarium(II) iodide on the product distribution were investigated. The racemic α-amino acids were obtained in up to 70% yield based on HPLC data. A novel approach to the synthesis ofα-amino acids is disclosed, involvingC-carboxylation of nitrones by gaseous CO2 under reductive coupling reaction conditions (SmI2, 0.1 M in THF) at ambient temperature and 50 bar of CO 2 pressure. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Aminophosphinic acids in a pyridine series, Part 2: Synthesis of 2-, 3-, and 4-pyridyl derivatives of 1-(Benzylamino)-methyl-H-phosphinic Acids

New 2-pyridyl, 3-pyridyl, and 4-pyridyl derivatives of 1-[N-(benzyl)amino]- methyl-H-phosphinic acid were prepared by the addition of bis(trimethylsilyl) phosphonite to the corresponding imines and subsequent methanolysis of the addition products. Treatment of the 2-pyridyl- and 1-(4-pyridyl)-1-(benzylamino) -methyl-H-phosphinic acids with aqueous mineral acids leads to cleavage and formation of the corresponding secondary amines and phosphorous acid (H3PO3).