73448-32-5Relevant articles and documents
Synthesis of 2-[(2-pyridyl)amino]ethyl β-D-lactosaminide and evaluation of its acceptor ability for sialyltransferase: A comparison with 4-methylumbelliferyl and dansyl β-D-lactosaminide
Kajihara, Yasuhiro,Kamiyama, Daisuke,Yamamoto, Naoki,Sakakibara, Tohru,Izumi, Masayuki,Hashimoto, Hironobu
, p. 1545 - 1550 (2004)
We reported the synthesis of β-D-lactosaminide with a 2-aminopyridyl group that is linked to a glycosyl tether at the reducing end. This fluorescent disaccharide acts as an acceptor for both α-(2→6)- and α-(2→3)-sialyltransferases. In addition, the acceptor ability of this disaccharide was evaluated and compared with that of β-D-lactosaminide having a dansyl or a 4-methylumbelliferyl group.
Highly efficient chemoenzymatic synthesis of β1-4-linked galactosides with promiscuous bacterial β1-4-galactosyltransferases
Lau, Kam,Thon, Vireak,Yu, Hai,Ding, Li,Chen, Yi,Muthana, Musleh M.,Wong, Denton,Huang, Ronald,Chen, Xi
supporting information; experimental part, p. 6066 - 6068 (2010/10/20)
Two bacterial β1-4-galactosyltransferases, NmLgtB and Hp1-4GalT, exhibit promiscuous and complementary acceptor substrate specificity. They have been used in an efficient one-pot multienzyme system to synthesize LacNAc, lactose, and their derivatives including those containing negatively charged 6-O-sulfated GlcNAc and C2-substituted GlcNAc or Glc, from monosaccharide derivatives and inexpensive Glc-1-P.
