73536-95-5 Usage
Description
ADENOSINE 5'-O-(2-THIODIPHOSPHATE) TRILITHIUM SALT is a chemical compound that is used in scientific research and experiments. It is a modified form of adenosine 5'-diphosphate (ADP), where one of the phosphate groups is replaced with a thiophosphate group. This modification makes it a useful tool for studying the effects of ADP on various biological processes.
Uses
Used in Neuroscience Research:
ADENOSINE 5'-O-(2-THIODIPHOSPHATE) TRILITHIUM SALT is used as a research tool for inducing neuropathic pain in rats. This allows scientists to study the effects of dorsal horn cannabinoid CB2 receptor activation on the expression of P2Y12 and P2Y13 (purinoceptors) receptors, which are involved in pain signaling and transmission.
Purification Methods
Purify it by ionexchange chromatography on DEAE-Sephadex A-25 using gradient elution with 0.1-0.5M triethylammonium bicarbonate. [Goody et al. Biochem Biophys Acta 276 155 1972.]
Check Digit Verification of cas no
The CAS Registry Mumber 73536-95-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,5,3 and 6 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 73536-95:
(7*7)+(6*3)+(5*5)+(4*3)+(3*6)+(2*9)+(1*5)=145
145 % 10 = 5
So 73536-95-5 is a valid CAS Registry Number.