736080-30-1Relevant articles and documents
PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIMIDINES
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Page/Page column 0279, (2015/02/02)
This invention relates to an improved process of making compounds of Formula (I) and synthetic intermediates thereof. (I) In particular, the invention relates to an improved process to prepare N-(2-aminophenyl)-4- ((pyrimidin-2-ylamino)methyl)benzamides which requires fewer steps, is efficient, can be used on an industrial scale, and results in a final product which is suitable for pharmaceutical use.
INHIBITORS OF HISTONE DEACETYLASE
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Page/Page column 65-66, (2010/02/14)
The invention relates to a series of compounds useful for inhibiting histone deacetylase (HDAC) enzymatic activity. The invention also provides a method for inhibiting histone descetylase in a cell using said compounds as well as a method for treating cell proliferative diseases and conditions using said HDAC inhibitors. Further, the invention provides pharmaceutical compositions comprising the HDAC inhibiting compounds and a pharmaceutically acceptable carrier.
Synthesis of esters of guanidinobenzoic acids and guanidinomethylbenzoic acids with antiproteolytic activity
Wagner,Vieweg,Kuehmstedt
, p. 293 - 296 (2007/10/06)
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