737000-80-5 Usage
Description
(R)-(-)-1-(4-CHLOROPHENYL)ETHYL ISOTHIOCYANATE, with the chemical formula C10H8ClNS, is an isothiocyanate compound characterized by a sulfur atom bonded to an isocyanate group. It is recognized for its strong, pungent odor and is primarily utilized in the synthesis of various organic compounds. (R)-(-)-1-(4-CHLOROPHENYL)ETHYL ISOTHIOCYANATE also serves as a reagent for the preparation of thiosemicarbazones and dithiocarbamates. Furthermore, it has garnered interest for its potential anti-tumor properties and its ability to inhibit the growth of cancerous cells. However, due to its high reactivity, it is crucial to handle (R)-(-)-1-(4-CHLOROPHENYL)ETHYL ISOTHIOCYANATE with care to avoid skin, eye, and respiratory tract irritation.
Uses
Used in Chemical Synthesis:
(R)-(-)-1-(4-CHLOROPHENYL)ETHYL ISOTHIOCYANATE is used as a key intermediate in the chemical synthesis of various organic compounds, contributing to the development of new molecules with diverse applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (R)-(-)-1-(4-CHLOROPHENYL)ETHYL ISOTHIOCYANATE is used as a reagent for the preparation of thiosemicarbazones and dithiocarbamates, which are important classes of compounds with potential applications in medicine.
Used in Cancer Research:
(R)-(-)-1-(4-CHLOROPHENYL)ETHYL ISOTHIOCYANATE is used as a research compound for studying its potential anti-tumor properties and its ability to inhibit the growth of cancerous cells, with the aim of developing novel therapeutic strategies against cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 737000-80-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,3,7,0,0 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 737000-80:
(8*7)+(7*3)+(6*7)+(5*0)+(4*0)+(3*0)+(2*8)+(1*0)=135
135 % 10 = 5
So 737000-80-5 is a valid CAS Registry Number.
737000-80-5Relevant articles and documents
Synthesis and antitumor activity of optically active thiourea and their 2-aminobenzothiazole derivatives: A novel class of anticancer agents
Manjula,Malleshappa Noolvi,Vipan Parihar,Manohara Reddy,Ramani, Vijay,Gadad, Andanappa K.,Singh, Gurdial,Gopalan Kutty,Mallikarjuna Rao
experimental part, p. 2923 - 2929 (2009/09/30)
A novel series of optically active 2-aminobenzothiazole derivatives were synthesized by reaction of optically active amine (I) with thiophosgene to obtain optically active isothiocyanates (IIa-h) which on condensation with 4-fluoro-3-chloro aniline (III)
