7379-12-6

Basic information

• Product Name: 2-Methyl-3-hexanone
• Synonyms: ISOPROPYL N-PROPYL KETONE;ISOPROPYL-PROPYL KETONE;2-METHYL-3-HEXANONE;N-PROPYL ISOPROPYL KETONE;2-methyl-3-hexanon;2-methyl-hexan-3-one;2-Methylhexan-3-one;3-Hexanone,2-methyl-
• CAS NO: 7379-12-6
• Molecular Formula: C₇H₁₄O
• Molecular Weight: 114.19
• EINECS: 230-940-9
• Product Categories: C7 to C8;Carbonyl Compounds;Ketones
• Mol File: 7379-12-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: -46.2°C (estimate)
• Boiling Point: 131-132 °C(lit.)
• Flash Point: 75 °F
• Appearance: Clear, colorless to slightly yellow liquid
• Density: 0.825 g/mL at 25 °C(lit.)
• Vapor Pressure: 8.15mmHg at 25°C
• Refractive Index: n20/D 1.406(lit.)
• CAS DataBase Reference: 2-Methyl-3-hexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-3-hexanone(7379-12-6)
• EPA Substance Registry System: 2-Methyl-3-hexanone(7379-12-6)

Safety Data

• Statements: 10
• Safety Statements: 16-29-33
• RIDADR: UN 1224 3/PG 3
• WGK Germany: 3
• RTECS: MP3900000
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 7379-12-6(Hazardous Substances Data)

Usage

Chemical Properties

Clear, colorless to slightly yellow liquid

Synthesis Reference(s)

Tetrahedron Letters, 10, p. 23, 1969 DOI: 10.1017/S0009838800024678

InChI:InChI=1/C7H14O/c1-4-5-7(8)6(2)3/h6H,4-5H2,1-3H3

Upstream product

• 1838-82-0 (±)-2-methylhex-1-en-3-ol 
• 617-29-8 2-methylhexan-3-ol 
• 54285-47-1 ethyl 2-ethyl-4-methyl-3-oxopentanoate 
• 15721-20-7 diisopropyl cadmium 
• 141-75-3 butyryl chloride 
• 38614-18-5 isopropylzinc iodide 
• 927-77-5 n-propylmagnesium bromide 
• 24470-78-8 isopropyltriphenylphosphonium iodide 
• 541-41-3 chloroformic acid ethyl ester 
• 187737-37-7 propene 
• 201230-82-2 carbon monoxide 
• 344746-83-4 2-ethyl-3-isopropyl-2,3-epoxypropionic acid 
• 60-29-7 diethyl ether 
• 63289-89-4 5-methyl-hexane-2,4-dione 2-enol tautomer 

Downstream Products

• 617-29-8 2-methylhexan-3-ol 
• 51200-82-9 4-isopropyl-heptan-4-ol 
• 93738-94-4 2-chloro-β,β-dimethylstyrene 
• 79-31-2 isobutyric Acid 
• 107-92-6 butyric acid 
• 1575700-90-1 (E)-N-[2-ethyl-3-(methoxyimino)hexyl]-4-methylbenzenesulfonamide 
• 109530-78-1 (1S,6S)-6-Ethyl-1-ethynyl-2,2-dimethyl-cyclohexanol 
• 109530-77-0 (1S,6R)-6-Ethyl-1-ethynyl-2,2-dimethyl-cyclohexanol 
• 79893-64-4 2-ethyl-6,6-dimethyl-1-cyclohexanone 
• 638-11-9 isopropyl butyrate 
• 82145-67-3 2-ethyl-4-methyl-1-phenyl-1,3-pentanedione 
• 67-64-1 acetone 
• 79893-66-6 2-ethyl-6,6-dimethylcyclohex-2-en-1-one 

Relevant articles and documents

Site-selective oxidation of unactivated C sp 3-H bonds with hypervalent iodine(III) reagents

By design: The site-selective oxidation of unactivated secondary C sp 3-H bonds was accomplished with hypervalent iodine(III) reagents and tert-butyl hydroperoxide (see scheme). The preparation and derivatization of the hypervalent iodine(III) reagent are simple, thus allowing the rational design of these reagents to optimize the site selectivity of the oxidation. Copyright

Rhodium Zeolites as Bifunctional Catalysts for the Synthesis of 2-Methylhexan-3-one and Heptan-4-one from Propylene, Carbon Monoxide, and Hydrogen

RhNaX and RhNaY zeolites behave as bifunctional catalysts for the synthesis of C7 ketones from C3H6, CO, and H2 at atmospheric pressure and 120-150 deg C.

A Palladium-Catalyzed Synthesis of Ketones from Acid Chlorides and Organozinc Compounds

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