7390-78-5

Basic information

• Product Name: H-TYR-TYR-TYR-OH
• Synonyms: L-TYR-TYR-TYR;H-TYR-TYR-TYR-OH;TYR-TYR-TYR;(S)-2-((S)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(4-hydroxyphenyl)propanamido)-3-(4-hydroxyphenyl)propanoic acid;REF DUPL: H-Tyr-Tyr-Tyr-OH;L-Tyrosyl-L-tyrosyl-L-tyrosine
• CAS NO: 7390-78-5
• Molecular Formula: C₂₇H₂₉N₃O₇
• Molecular Weight: 507.54
• Product Categories: Dipeptides and Tripeptides;Peptides;Tripeptides
• Mol File: 7390-78-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 940.6±65.0 °C(Predicted)
• Appearance: /
• Density: 1.387±0.06 g/cm3(Predicted)
• Storage Temp.: −20°C
• PKA: 3.07±0.10(Predicted)
• CAS DataBase Reference: H-TYR-TYR-TYR-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-TYR-TYR-TYR-OH(7390-78-5)
• EPA Substance Registry System: H-TYR-TYR-TYR-OH(7390-78-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 7390-78-5(Hazardous Substances Data)

Usage

General Description

H-TYR-TYR-TYR-OH, also known as tripeptide tyrosine, is a chemical compound composed of three molecules of the amino acid tyrosine linked together. Tyrosine is an important amino acid involved in the production of several key neurotransmitters and hormones in the body, including dopamine, adrenaline, and thyroid hormones. As a tripeptide, H-TYR-TYR-TYR-OH may have potential applications in the field of pharmaceuticals and biotechnology due to its ability to modulate physiological processes and potentially influence the function of the central nervous system. Additionally, research suggests that tyrosine derivatives may have antioxidant and anti-inflammatory properties, making H-TYR-TYR-TYR-OH a potential candidate for further exploration in drug development and therapeutic interventions.

Upstream product

• 618116-00-0 N-benzyloxycarbonyl-L-tyrosyl-L-tyrosyl-L-tyrosine 
• 51514-08-0 O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride 
• 51514-13-7 O-acetyl-N-benzyloxycarbonyl L-tyrosine 
• 42406-77-9 L-tyrosine benzyl ester 
• 1080-06-4 L-Tyr-OMe 
• 4985-46-0 L-Tyr-NH₂ 

Relevant articles and documents

Peptide bond formation by aminolysin-A catalysis: A simple approach to enzymatic synthesis of diverse short oligopeptides and biologically active puromycins

A new S9 family aminopeptidase derived from the actinobacterial thermophile Acidothermus cellulolyticus was cloned and engineered into a transaminopeptidase by site-directed mutagenesis of catalytic Ser491 into Cys. The engineered biocatalyst, designated aminolysin-A, can catalyze the formation of peptide bonds to give linear homo-oligopeptides, hetero-dipeptides, and cyclic dipeptides using cost-effective substrates in a one-pot reaction. Aminolysin-A can recognize several C-terminal-modified amino acids, including the l- and d-forms, as acyl donors as well as free amines, including amino acids and puromycin aminonucleoside, as acyl acceptors. The absence of amino acid esters prevents the formation of peptides; therefore, the reaction mechanism involves aminolysis and not a reverse reaction of hydrolysis. The aminolysin system will be a beneficial tool for the preparation of structurally diverse peptide mimetics by a simple approach.