73936-73-9

Basic information

• Product Name: 5-AZIDONAPHTHALENE-1-SULFONYL CHLORIDE
• Synonyms: 5-AZIDONAPHTHALENE-1-SULFONYL CHLORIDE;5-azido-1-Naphthalenesulfonyl chloride
• CAS NO: 73936-73-9
• Molecular Formula: C₁₀H₆ClN₃O₂S
• Molecular Weight: 267.69
• Mol File: 73936-73-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-AZIDONAPHTHALENE-1-SULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AZIDONAPHTHALENE-1-SULFONYL CHLORIDE(73936-73-9)
• EPA Substance Registry System: 5-AZIDONAPHTHALENE-1-SULFONYL CHLORIDE(73936-73-9)

Safety Data

• Hazardous Substances Data: 73936-73-9(Hazardous Substances Data)

Usage

General Description

5-AZIDONAPHTHALENE-1-SULFONYL CHLORIDE is a chemical compound with the formula C10H6N3O2SCl. It is a derivative of naphthalene and contains a sulfonamide group and an azide group. 5-AZIDONAPHTHALENE-1-SULFONYL CHLORIDE is commonly used in organic synthesis as a reagent for introducing the azide group into various molecules. It is also used in the preparation of fluorescent dyes and labels for biological labeling and imaging applications. Additionally, 5-AZIDONAPHTHALENE-1-SULFONYL CHLORIDE has potential uses in medicinal chemistry for developing new drugs and pharmaceuticals. However, it is important to handle this compound with caution due to its potential hazards and reactivity.

InChI:InChI=1/C10H6ClN3O2S/c11-17(15,16)10-6-2-3-7-8(10)4-1-5-9(7)13-14-12/h1-6H

Upstream product

• 84-89-9 1-aminonaphthalene-5-sulfonic acid 
• 73105-93-8 1-Azido-5-naphtalene sulfonate 

Downstream Products

• 680573-19-7 5-azidonaphthalene-1-sulfonamidoethyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->2)-3,4,6-tri-O-benzoyl-α-D-mannopyranoside 
• 680573-15-3 5-azidonaphthalene-1-sulfonamidoethyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside 

Relevant articles and documents

Demonstration of direct binding of cIAP1 degradation-promoting bestatin analogs to BIR3 domain: Synthesis and application of fluorescent bestatin ester analogs

Overexpression of cIAP1 correlates with resistance to radiotherapy and chemotherapy in various cancers. Recently, we reported that a class of bestatin ester analogs represented by MeBS (2) destabilized and promoted the degradation of cIAP1 through auto-ub

Preparation and Characterization of Photoactivable Heterobifunctional Fluorescent Reagents

Two new photoactivable heterobifunctional reagents, 1-azido-5-naphthalene sulfonyl chloride (ANS-Cl) and the N-hydroxysuccinimide ester of 1-azido-5-naphthalene sulfonyl aminopropionate (NHS-ANS-AP), were synthesized and characterized.The reagents were applicable to the group-directed modification of ligands.Upon exposure to ultraviolet light, non-fluorescent modified ligands generated reactive nitrene intermediates which could react with neighboring molecules to form fluorescent products.This was demonstrated by the covalent modification of bovine serum albumin with ANS-AP by photolysis.NHS-ANS-AP was used for the preparation of a photoreactive invertebrate lectin.