7398-82-5

Basic information

• Product Name: alpha,alpha,alpha',alpha'-Tetrachloro-p-xylene
• Synonyms: alpha,alpha,alpha',alpha'-Tetrachloro-p-xylene;1,4-Di(dichloromethyl)benzene;α,α,α',α'-Tetrachloro-p-xylene;ALPHA,ALPHA,ALPHA',ALPHA'-TETRACHLORO-PARA-XYLENE
• CAS NO: 7398-82-5
• Molecular Formula: C₈H₆Cl₄
• Molecular Weight: 243.94524
• EINECS: 230-994-3
• Mol File: 7398-82-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 9.5°C
• Boiling Point: 272.29°C (estimate)
• Flash Point: 140.4 °C
• Appearance: /
• Density: 1.6060
• Vapor Pressure: 0.00173mmHg at 25°C
• Refractive Index: 1.5149 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: alpha,alpha,alpha',alpha'-Tetrachloro-p-xylene(CAS DataBase Reference)
• NIST Chemistry Reference: alpha,alpha,alpha',alpha'-Tetrachloro-p-xylene(7398-82-5)
• EPA Substance Registry System: alpha,alpha,alpha',alpha'-Tetrachloro-p-xylene(7398-82-5)

Safety Data

• Hazardous Substances Data: 7398-82-5(Hazardous Substances Data)

Usage

General Description

Alpha, alpha, alpha', alpha'-Tetrachloro-p-xylene (ATCX) is a chlorinated derivative of p-xylene, a colorless, sweet-smelling liquid and an important compound in the chemical industry. ATCX is a crystalline solid at room temperature. It is mainly used in organic synthesis and as a reactant for the production of other chemical compounds. Not much is known about its hazards or toxicity, however, due to its chemical similarity with chlorinated hydrocarbons, it may cause toxic effects upon ingestion, inhalation, or skin contact. It may also have environmental impacts if it enters water bodies due to its potential for bioaccumulation.

InChI:InChI=1/C8H6Cl4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4,7-8H

Upstream product

• 106-42-3 para-xylene 
• 7782-50-5 chlorine 
• 77072-05-0 4-dichloromethyl benzaldehyde 
• 623-27-8 terephthalaldehyde, 

Downstream Products

• 55591-48-5 1,4-bis(dimorpholinomethyl)benzene 
• 369-54-0 p-bis(difluoromethyl)benzene 
• 909006-03-7 α,α-dichloro, α',α'-difluoro-p-xylene 
• 623-27-8 terephthalaldehyde, 
• 17557-10-7 α,α,α',α'-tetrakis(trimethylsilyl)-1,4-xylol 

Relevant articles and documents

Formamide Catalysis Facilitates the Transformation of Aldehydes into Geminal Dichlorides

Herein, a novel method for the transformation of aldehydes into geminal dichlorides based on phthaloyl chloride as reagent and N -formylpyrrolidine as Lewis base catalyst is disclosed. Given the mild reaction conditions, the current protocol is distinguished by high levels of functional group compatibility and scalability and is operationally simple. The in situ formation of a Vilsmeier Haack reagent type intermediate is likely to be essential for this organocatalytic nucleophilic substitution reaction.

METHOD FOR THE PREPARATION OF ALPHA, ALPHA, ALPHA', ALPHA'-TETRACHLORO-P-XYLENE

A synthesis method of α,α,α′,α′-tetrachloro-p-xylene is disclosed. The method includes reacting terephthaldicarboxaldehyde with a mixture of SOCl2 and dimethylformamide (DMF) to obtain a product mixture containing α,α,α′,α′-tetrachloro-p-xylene as a major product and 4-dichloromethyl benzaldehyde as a side product, which can be separated by silica column chromatography.

Conversion of aromatic aldehydes to gem-dichlorides using boron trichloride. A new highly efficient method for preparing dichloroarylmethanes

The chlorination of aromatic aldehydes with boron trichloride in hexane under reflux conditions produces the corresponding dichloromethyl derivatives in excellent yields. (C) 2000 Elsevier Science Ltd.