74-95-3

Basic information

• Product Name: Dibromo methane
• Synonyms: Methylene bromide;Methylene dibromide;NSC 7293;Dibromomethane [UN2664] [Poison];Methane, dibromo-
• CAS NO: 74-95-3
• Molecular Formula: CH₂Br₂
• Molecular Weight: 173.85
• EINECS: 200-824-2
• Mol File: 74-95-3.mol
• Article Data: 41

Chemical Properties

• Melting Point: -52℃
• Boiling Point: 97 °C at 760 mmHg
• Flash Point: 96-98 °C
• Appearance: colourless liquid
• Density: 2.434 g/cm³
• Vapor Pressure: 48.7mmHg at 25°C
• Refractive Index: 1.532
• Water Solubility: 0.1 g/100 mL (20℃)
• CAS DataBase Reference: Dibromo methane(CAS DataBase Reference)
• NIST Chemistry Reference: Dibromo methane(74-95-3)
• EPA Substance Registry System: Dibromo methane(74-95-3)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: R20:; R52/53:
• Safety Statements: S24:; S61:
• RIDADR: 2664
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 74-95-3(Hazardous Substances Data)

Usage

InChI:InChI=1/CH2Br2/c2-1-3/h1H2

Synthetic route

Bromoform (75-25-2) + trimethylsilyl bromide (2857-97-8) → trimethyl-tribromomethyl-silane (18142-75-1) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
With hexaethylphosphoric triamide In diethyl ether at 20℃; for 1h;	A 82% B n/a

bis(thiocyanato)methane (6317-18-6) + sodium thiocyanide (540-72-7) → 1,2-dibromomethane (74-95-3)

Conditions	Yield
Stage #1: bis(thiocyanato)methane; sodium thiocyanide In methanol; water at 74 - 75℃; for 5h; Stage #2: With sodium hydrogencarbonate In methanol; water pH=6.3; Concentration; Solvent;	79.3%

methane (34557-54-5) → methyl bromide (74-83-9) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
With bromine at 18 - 500℃; for 0.0166667h; Gas phase;	A 70.6% B 24.7%
With hydrogen bromide; oxygen; Mg/Ru/SiO2 In water at 580℃; Conversion of starting material;
With hydrogen bromide; oxygen; Ba/Bi/Ru/SiO2 In water at 580 - 600℃; Conversion of starting material;

dichloromethane (75-09-2) → chlorobromomethane (74-97-5) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
With calcium bromide; tetrahexylammonium bromide at 110℃; for 24h;	A 30% B 62%
With ethyl bromide; aluminum oxide; tetrabutyl phosphonium bromide at 170℃;	A 49 % Spectr. B 25 % Spectr.
With ethyl bromide at 170℃; Product distribution; var. of catalyst, reagent;	A 50 % Spectr. B 24 % Spectr.
With ethyl bromide; aluminum oxide at 170℃;	A 66 % Spectr. B 14 % Spectr.

2-ethoxy-1,3-dioxane (76508-46-8) + Bromoform (75-25-2) → trimethylene carbonate (2453-03-4) + ethyl bromide (74-96-4) + 3-Brompropylformiat (53452-10-1) + acetaldehyde (75-07-0) + 3-bromopropyl ethyl carbonate + 1,2-dibromomethane (74-95-3)

Conditions	Yield
dibenzoyl peroxide at 100℃; for 2h; Rate constant; Product distribution; other temperature;	A n/a B n/a C n/a D n/a E 60% F n/a

Bromoform (75-25-2) + 2-(hexyloxy)-1,3-dioxolane (83498-70-8) → [1,3]-dioxolan-2-one (96-49-1) + 1-bromo-hexane (111-25-1) + formic acid-(2-bromo-ethyl ester) (6065-67-4) + hexanal (66-25-1) + 2-bromoethyl hexyl carbonate + 1,2-dibromomethane (74-95-3)

Conditions	Yield
dibenzoyl peroxide at 100℃; for 2h; Rate constant; Product distribution; other temperature;	A n/a B n/a C n/a D n/a E 60% F n/a

chloro-trimethyl-silane (75-77-4) + Bromoform (75-25-2) → trimethyl-tribromomethyl-silane (18142-75-1) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
With hexaethylphosphoric triamide In diethyl ether at 20℃; for 1h;	A 56% B n/a

Bromoform (75-25-2) + 2-(hexyloxy)-m-dioxane → trimethylene carbonate (2453-03-4) + 1-bromo-hexane (111-25-1) + 3-Brompropylformiat (53452-10-1) + hexanal (66-25-1) + 3-bromopropyl hexyl carbonate + 1,2-dibromomethane (74-95-3)

Conditions	Yield
dibenzoyl peroxide at 100℃; for 2h; Rate constant; Product distribution; other temperature;	A n/a B n/a C n/a D n/a E 56% F n/a

methane (34557-54-5) → methyl bromide (74-83-9) + Bromoform (75-25-2) + carbon tetrabromide (558-13-4) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
With bromine at 500℃; Product distribution; Further Variations:; Temperatures; Bromination;	A 17.4% B 0.48% C 2.5% D 5%

methyl bromide (74-83-9) → 1,2-dibromomethane (74-95-3)

Conditions	Yield
With bromine at 250℃;

n-butyllithium (109-72-8, 29786-93-4) + carbon tetrabromide (558-13-4) → 1,2-dibromomethane (74-95-3)

Conditions	Yield
at -50℃;

methylene (2465-56-7) + Bromoform (75-25-2) → 1,2-dibromomethane (74-95-3)

methylene (2465-56-7) + dibromodichloromethane (594-18-3) → 1,1-Dichloroethylene (75-35-4) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
Tetrabrommethan,Bromoform und Jodoform reagieren analog;

diiodomethane (75-11-6) → 1,2-dibromomethane (74-95-3)

Conditions	Yield
With water; bromine
With bromine

methane (34557-54-5) → Bromoform (75-25-2) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
With bromine at 400℃;

dichloromethane (75-09-2) → 1,2-dibromomethane (74-95-3)

Conditions	Yield
With aluminum tri-bromide
With aluminum tri-bromide; hydrogen bromide
With bromine; aluminium

chlorobromomethane (74-97-5) → 1,2-dibromomethane (74-95-3)

Conditions	Yield
With bromine; aluminium

Bromoform (75-25-2) + potassium tert-butylate (865-47-4) → 1,2-dibromomethane (74-95-3)

Bromoform (75-25-2) + ethylmagnesium bromide (925-90-6) → ethyl bromide (74-96-4) + methane (34557-54-5) + 3-ethylpentane (617-78-7) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
Produkt: Aethan, Acetylen;

Bromoform (75-25-2) → 1,2-dibromomethane (74-95-3)

Conditions	Yield
With alkali sulfite
With phenylhydrazine
With alkaline potassium arsenite man destilliert das Reaktionsprodukt mit Wasserdampf;

2,2,5,5-tetrabromo-1,6-diphenyl-hexane-1,3,4,6-tetraone (861525-37-3) + furan-2,3,5(4H)-trione pyridine (1:1) → oxalic acid (144-62-7) + benzoic acid (65-85-0) + 1,2-dibromomethane (74-95-3)

acetic acid (64-19-7) → 1,2-dibromomethane (74-95-3)

Conditions	Yield
With bromine; pyrographite at 300℃;

bromoacetic acid (79-08-3) → 1,2-dibromomethane (74-95-3)

Conditions	Yield
Electrolysis;

methylene (2465-56-7) + dibromodichloromethane (594-18-3) + chlorobenzene (108-90-7) → 1,1-Dichloroethylene (75-35-4) + 1,2-dibromomethane (74-95-3)

methylene (2465-56-7) + carbon tetrabromide (558-13-4) + chlorobenzene (108-90-7) → vinylidene dibromide (593-92-0) + 1,2-dibromomethane (74-95-3)

Bromoform (75-25-2) + phenylhydrazine (100-63-0) → formic acid (64-18-6) + 1,2-dibromomethane (74-95-3)

2-ethoxy-1,3-dioxolane (4544-20-1) + Bromoform (75-25-2) → [1,3]-dioxolan-2-one (96-49-1) + ethyl bromide (74-96-4) + formic acid-(2-bromo-ethyl ester) (6065-67-4) + 2-bromoethyl ethyl carbonate (36842-22-5) + acetaldehyde (75-07-0) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
With dibenzoyl peroxide at 90℃; for 0.5h; Product distribution;
dibenzoyl peroxide at 100℃; for 2h; Rate constant; Product distribution; other temperature, other time;

1-bromo-butane (109-65-9) + dichloromethane (75-09-2) → chlorobromomethane (74-97-5) + n-Butyl chloride (109-69-3) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
aluminum oxide; tetrabutyl phosphonium bromide In gas at 150℃; Product distribution; effect of catalytic bed;

2-phenyl-1,3-oxathiolane (5721-88-0) → 1,1,2,2-tetrabromoethane (79-27-6) + S-(2-bromoethyl) benzothioate (81110-22-7) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
With Bromoform; di-tert-butyl peroxide at 130℃; for 4.5h; Yields of byproduct given;	A n/a B 16 % Turnov. C n/a

ethyl bromide (74-96-4) + dichloromethane (75-09-2) → chloroethane (75-00-3) + chlorobromomethane (74-97-5) + 1,2-dibromomethane (74-95-3)

Conditions	Yield
aluminum oxide; tetrabutyl phosphonium bromide In gas at 150℃; Product distribution; effect of catalytic bed;

carbon dioxide (124-38-9) + 1,2-dibromomethane (74-95-3) → dibromoacetic acid (631-64-1)

Conditions	Yield
Stage #1: 1,2-dibromomethane With 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex In tetrahydrofuran; toluene at -78℃; for 0.5h; Inert atmosphere; Stage #2: carbon dioxide In tetrahydrofuran; toluene at -78℃; for 3h;	100%
(i) nBuLi, CH2Cl2, THF, (ii) /BRN= 1900390/; Multistep reaction;

Quinuclidine (100-76-5) + 1,2-dibromomethane (74-95-3) → 1-Bromomethyl-1-azonia-bicyclo[2.2.2]octane; bromide (104303-96-0)

Conditions	Yield
In acetonitrile at 30℃; under 750.06 Torr; for 3h;	100%

2-tert-butylcyclopentanone (40557-24-2) + 1,2-dibromomethane (74-95-3) → 1-tert-butyl-2-methylene-cyclopentane (66228-12-4)

Conditions	Yield
With titanium tetrachloride; zinc In dichloromethane	100%

(S)-1,2,3,10,11,12-Hexamethoxy-7-methyl-7,8-dihydro-5H-dibenzo[a,c]cycloocten-6-one (130611-53-9, 130695-96-4) + 1,2-dibromomethane (74-95-3) → (S)-1,2,3,10,11,12-Hexamethoxy-6-methyl-7-methylene-5,6,7,8-tetrahydro-dibenzo[a,c]cyclooctene (114394-15-9, 130695-98-6, 135095-47-5)

Conditions	Yield
With titanium tetrachloride; zinc In dichloromethane for 0.25h; Ambient temperature;	100%

(4aR,6S,7R,8aS)-4-(4-methoxybenzyloxy)butyric acid 2,2-di(tert-butyl)-6-methyl-6-(2-methylallyl)-4,4a,6,7,8,8a-hexahydro-1,3,5-trioxa-2-silanaphthalen-7-yl ester (511256-85-2) + 1,2-dibromomethane (74-95-3) → (4aR,6S,7R,8aS)-2,2-di(tert-butyl)-7-{1-[3-(4-methoxybenzyloxy)propyl]vinyloxy}-6-methyl-6-(2-methylallyl)-4,4a,6,7,8,8a-hexahydro-1,3,5-trioxa-2-silanaphthalene (511256-86-3)

Conditions	Yield
With N,N,N,N,-tetramethylethylenediamine; titanium tetrachloride; zinc; lead(II) chloride In tetrahydrofuran; dichloromethane for 2h; Heating;	100%

1-benzylimidazole (4238-71-5) + 1,2-dibromomethane (74-95-3) → 1,1’-dibenzyl-3,3’-methylenediimidazolium dibromide

Conditions	Yield
In tetrahydrofuran at 100℃;	100%
Inert atmosphere; Schlenk technique;	99%
at 70 - 80℃;	81%

5,5,9-trimethylspiro<5.5>undec-8-en-1-one (133545-69-4) + 1,2-dibromomethane (74-95-3) → 3,7,7-trimethyl-11-methylenespiro[5.5]undec-2-ene (15401-86-2)

Conditions	Yield
With titanium tetrachloride; zinc In dichloromethane at 0 - 20℃; for 3h;	100%

5,5-dimethoxypentanoic acid 2,2-di-tert-butyl-6-methyl-6-(2-methylallyl)-hexahydro-1,3,5-trioxa-2-sila-naphthalen-7-yl ester (943226-61-7) + 1,2-dibromomethane (74-95-3) → C27H50O6Si (1053270-93-1)

Conditions	Yield
With N,N,N,N,-tetramethylethylenediamine; titanium tetrachloride; zinc; lead(II) chloride In tetrahydrofuran; dichloromethane for 2h;	100%

4-[5-(3-benzyloxy-1-methylpropyl)-4-methyl-tetrahydro-furan-2-yl]-3-triisopropylsilanyloxy-butyric acid 2-but-3-enyl-10a,11a-dimethyl-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-3-yl ester (943226-85-5) + 1,2-dibromomethane (74-95-3) → C48H80O7Si

Conditions	Yield
With N,N,N,N,-tetramethylethylenediamine; titanium tetrachloride; zinc; lead(II) chloride In dichloromethane at 65℃;	100%

1-Butylimidazole (4316-42-1) + 1,2-dibromomethane (74-95-3) → 1,1’-di-n-butyl-3,3’-methylenediimidazolium dibromide

Conditions	Yield
In tetrahydrofuran at 100℃;	100%
Inert atmosphere; Schlenk technique;	89%
In tetrahydrofuran at 20 - 80℃; for 192h;	87.6%
In acetonitrile for 96h; Reflux;

C18H25BO3 + 1,2-dibromomethane (74-95-3) → C18H24BBrO3

Conditions	Yield
Stage #1: C18H25BO3; 1,2-dibromomethane With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h; Inert atmosphere; Stage #2: With zinc(II) chloride In tetrahydrofuran; diethyl ether at -78 - 20℃; Inert atmosphere; enantioselective reaction;	100%

vilmorrianine E + 1,2-dibromomethane (74-95-3) → N-bromomethyl vilmorrianine E hydrobromide

Conditions	Yield
In ethyl acetate for 120h; Reflux;	100%

diethyl tert-butoxycarbonylaminomalonate (102831-44-7) + 1,2-dibromomethane (74-95-3) → C13H22BrNO6

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; Inert atmosphere;	100%

3-formylphenyl acetate (34231-78-2) + 3-acetylbenzaldehyde (41908-11-6) + 1,2-dibromomethane (74-95-3) → 3-vinylphenyl acetate (2454-30-0)

Conditions	Yield
With acetic anhydride	99.7%

chloro-trimethyl-silane (75-77-4) + 1,2-dibromomethane (74-95-3) → dibromobis(trimethylsilyl)methane (29955-10-0)

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran; hexane; pentane 1.) -110 deg C, 20 min, 2.) -110 deg C to r.t., 12 h;	99%
With lithium diisopropyl amide In tetrahydrofuran at -78 - 20℃;	88%
With lithium diisopropyl amide In tetrahydrofuran at -100℃;	60%

(+)-(2,3-endo)-tert-butyldimethylsilyl 3-(1-oxopropyl)bicyclo<2.2.1>hept-5-ene-2-carboxylate (113352-74-2) + 1,2-dibromomethane (74-95-3) → (+)-(2,3-endo)-tert-butyldimethylsilyl 3-(1-methenylpropyl)bicyclo<2.2.1>hept-5-ene-2-carboxylate (113352-75-3)

Conditions	Yield
With titanium tetrachloride; zinc In tetrahydrofuran; dichloromethane at 20℃; for 0.5h;	99%

5'-(O-tert-butyl(dimethyl)silyl)-3'-ketothymidine (147043-60-5) + 1,2-dibromomethane (74-95-3) → 1-[(2R,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-methylene-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione (170638-74-1)

Conditions	Yield
With titanium tetrachloride; zinc In tetrahydrofuran; dichloromethane for 2h; Ambient temperature;	99%
With titanium tetrachloride; zinc In tetrahydrofuran; dichloromethane

1-methyl-1H-imidazole (616-47-7) + 1,2-dibromomethane (74-95-3) → 1,1'-dimethyl-3,3'-methylenediimidazolium bromide

Conditions	Yield
In tetrahydrofuran at 130℃; for 24h;	99%
Inert atmosphere; Schlenk technique;	99%
for 18h; Reflux;	96%

1,2-dibromomethane (74-95-3) + methyl 5,6-dihydroxy-2-thien-2-ylpyrimidine-4-carboxylate (391680-92-5) → 5-thiophen-2-yl-[1,3]dioxolo[4,5-d]pyrimidine-7-carboxylic acid methyl ester (766557-56-6)

Conditions	Yield
With potassium fluoride In N,N-dimethyl-formamide at 120℃;	99%

3-(5-chloro-2-methoxy-benzenesulfonylamino)-4-hydroxy-benzoic acid methyl ester (946121-16-0) + 1,2-dibromomethane (74-95-3) → 3-(5-chloro-2-methoxy-benzenesulfonyl)-2,3-dihydro-benzooxazole-5-carboxylic acid methyl ester (946121-17-1)

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 48h;	99%

indium(I) bromide + dimethyl sulfoxide (67-68-5) + 1,2-dibromomethane (74-95-3) → Br2InCH2Br*3(CH3)2SO (99666-59-8)

Conditions	Yield
In dimethyl sulfoxide DMSO added to suspn. of InBr in CH2Br2 at ca. -80°C, allowed to reach room temp. with stirring, further stirred for 1 h; evapd. in vac., oil solidified on stirring with petroleum ether, solid washed with Et2O, dried in vac.; elem. anal.;	99%

(CoH(NC5H4CH2CH2NHCH(CH3)C(CH3)NO)2)(2+) (185411-43-2) + 1,2-dibromomethane (74-95-3) → ((CH2)Co(NC5H4CH2CH2NHCH(CH3)C(CH3)NO)2)(1+)*ClO4(1-)=((CH2)Co(NC5H4CH2CH2NHCH(CH3)C(CH3)NO)2)ClO4 (377734-77-5)

Conditions	Yield
With NaBH4; PdCl2; NaOH In methanol; water soln. NaOH was added to suspn. Co(III) complex in MeOH under Ar, NaBH4 in water was added, PdCl2 in aq. HCl was added, after 15 min CH2Br2 was added;	99%

[Rh(triphenylphosphine)(C5Me5)((2,4,6-tri-tert-butylphenyl)phosphinidene)] (532932-53-9) + 1,2-dibromomethane (74-95-3) → (η5-C5Me5)Rh{PPh3}Br2

Conditions	Yield
In pentane byproducts: ((CH3)3C)3C6H2PCH2; (N2 or Ar); treatment of soln. of Rh(PPh3)(C5Me5)(PC6H2(t-Bu)3) in n-pentane with small excess of CH2Br2 at room temp. for 12 h; pptn., decanting, washing with n-pentane;	99%

triisopropylsilyl chloride (13154-24-0) + 1,2-dibromomethane (74-95-3) → (dibromomethyl)triisopropylsilane

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at -78 - 20℃; Inert atmosphere;	99%
With lithium diisopropyl amide In tetrahydrofuran at -78 - 20℃;	99%

(S)-6,6'-dimethyl-5,5'-dibromo-2,2'-dihydroxybiphenyl + 1,2-dibromomethane (74-95-3) → C15H12Br2O2

Conditions	Yield
With potassium carbonate In acetonitrile for 4h; Reflux;	99%

ethyl N-(2-iodophenyl)-N-(2-phenylacryloyl)glycinate + 1,2-dibromomethane (74-95-3) → ethyl 2-(2'-oxo-2,3-dihydrospiro[indene-1,3'-indolin]-1'-yl)acetate

Conditions	Yield
With palladium diacetate; tetra-(n-butyl)ammonium iodide; potassium carbonate; triethylamine; tris-(o-tolyl)phosphine In N,N-dimethyl acetamide at 90℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	99%

N-benzyl-N-(2-iodophenyl)-2-phenylacrylamide + 1,2-dibromomethane (74-95-3) → 1'-benzyl-2,3-dihydrospiro[indene-1,3'-indolin]-2'-one

Conditions	Yield
With palladium diacetate; tetra-(n-butyl)ammonium iodide; potassium carbonate; triethylamine; tris-(o-tolyl)phosphine In N,N-dimethyl acetamide at 90℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	99%

ethoxyethoxyethanol (111-90-0) + 1,2-dibromomethane (74-95-3) → 1,13-diethoxy-3,6,8,11-tetraoxa-tridecane (42598-91-4)

Conditions	Yield
With potassium hydroxide; tetrabutylammomium bromide In water; chlorobenzene at 50℃; for 0.5h;	98.58%

methyl 3-methylbutanoate (556-24-1) + 1,2-dibromomethane (74-95-3) → l-methyl dl-2,2-dimethylcyclopropane-1-carboxylate (932-58-1, 89312-78-7, 172419-34-0)

Conditions	Yield
With acetyl chloride; copper(l) chloride In dichloromethane for 12h; Reagent/catalyst; Reflux;	98.2%

benzoic acid (65-85-0) + 1,2-dibromomethane (74-95-3) → bis(benzoyloxy)methane (5342-31-4)

Conditions	Yield
With anion exchange resin for 5h; Heating;	98%
With sodium hydroxide

Upstream product

• 109-72-8 n-butyllithium 
• 558-13-4 carbon tetrabromide 
• 2465-56-7 methylene 
• 75-25-2 Bromoform 
• 594-18-3 dibromodichloromethane 
• 34557-54-5 methane 
• 75-09-2 dichloromethane 
• 74-97-5 chlorobromomethane 
• 865-47-4 potassium tert-butylate 
• 925-90-6 ethylmagnesium bromide 
• 64-19-7 acetic acid 
• 108-90-7 chlorobenzene 
• 74-96-4 ethyl bromide 
• 621-23-8 1,2,3-trimethoxybenzene 

Downstream Products

• 74-96-4 ethyl bromide 
• 5459-35-8 2-bromo-acrylic acid ethyl ester 
• 108-86-1 bromobenzene 
• 100-39-0 benzyl bromide 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 5398-65-2 1,1-dibromo-2-vinylcyclopropane 
• 90825-50-6 meso-2,4-dicyano-1,5-pentanedioic acid ethyl ester 
• 141-79-7 4-methyl-pent-3-en-2-one 
• 2568-36-7 6,6-dibromobicylo[3.1.0]hexane 
• 873377-01-6 bis-(4-acetylamino-phenylsulfanyl)-methane 
• 5422-70-8 1-bromo-N,N,N-trimethylmethaniminium bromide 
• 930-57-4 n-butylcyclopropane 
• 44860-68-6 Formaldehyde di-(2-hydroxyethyl) thioacetal 
• 631-64-1 dibromoacetic acid 

Relevant articles and documents

Occurrence of bromoperoxidase in the marine green macro-alga, ulvella lens, and emission of volatile brominated methane by the enzyme

Bromoperoxidase activity was detected in the marine green macro-alga, Ulvella lens, which is used to induce the larval metamorphosis of sea urchin in aquaculture in Japan. The enzyme activity was enhanced 8.5- and 2.2-fold by the addition of cobalt and vanadium ions to the reaction mixture, respectively. The volatile halogenated compounds dibromomethane and tribromomethane were formed in the reaction mixture when the enzyme was incubated with oxaloacetate, hydrogen peroxide and potassium bromide. These results suggest that dibromomethane, which was reported to be released by U. lens and play an important role as the inducer of larval settlement and metamorphosis, is produced by bromoperoxidase in the alga.

One-Pot Conversion of Methane to Light Olefins or Higher Hydrocarbons through H-SAPO-34-Catalyzed in Situ Halogenation

Methane was converted to light olefins (ethene and propene) or higher hydrocarbons in a continuous flow reactor below 375 °C over H-SAPO-34 catalyst via an in situ halogenation (chlorination/bromination) protocol. The reaction conditions can be efficiently tuned toward selective monohalogenation of methane to methyl halides or their in situ oligomerization to higher hydrocarbons. The presence of C5+ hydrocarbons in the reaction products clearly indicates that by using a properly engineered catalyst under optimized reaction conditions, hydrocarbons in the gasoline range can be produced. This approach has significant potential for feasible application in natural gas refining to gasoline and materials under moderate operational conditions.

PROCESS FOR MANUFACTURING METHYLENE BIS(THIOCYANATE)

This invention provides pure methylene bis(thiocyanate) in an ecor industrial process. The product is practically free of insolubles (0.1%) after prolonged storage.