74032-89-6 Usage
General Description
NEUROTENSIN (1-11) is a peptide fragment derived from the larger neurotensin protein that acts as a neurotransmitter in the brain and central nervous system. It plays a role in regulating a variety of physiological processes, including pain perception, temperature regulation, and gastrointestinal function. NEUROTENSIN (1-11) has been shown to be involved in the modulation of dopamine signaling, as well as in the regulation of motivation and reward pathways in the brain. Studies have also suggested potential therapeutic applications for NEUROTENSIN (1-11), particularly in the treatment of neurological and psychiatric disorders. Overall, NEUROTENSIN (1-11) is a biologically active chemical that has important implications for understanding brain function and developing new treatments for neurological and psychiatric conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 74032-89-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,0,3 and 2 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 74032-89:
(7*7)+(6*4)+(5*0)+(4*3)+(3*2)+(2*8)+(1*9)=116
116 % 10 = 6
So 74032-89-6 is a valid CAS Registry Number.
InChI:InChI=1/C66H99N19O18/c1-35(2)31-45(80-55(93)41-22-24-52(89)75-41)57(95)81-46(32-36-14-18-38(86)19-15-36)58(96)76-42(23-25-53(90)91)56(94)82-47(34-51(68)88)59(97)79-43(9-3-4-26-67)62(100)84-29-7-12-49(84)60(98)77-40(10-5-27-73-65(69)70)54(92)78-44(11-6-28-74-66(71)72)63(101)85-30-8-13-50(85)61(99)83-48(64(102)103)33-37-16-20-39(87)21-17-37/h14-21,35,40-50,86-87H,3-13,22-34,67H2,1-2H3,(H2,68,88)(H,75,89)(H,76,96)(H,77,98)(H,78,92)(H,79,97)(H,80,93)(H,81,95)(H,82,94)(H,83,99)(H,90,91)(H,102,103)(H4,69,70,73)(H4,71,72,74)/t40-,41-,42-,43-,44-,45-,46-,47-,48+,49-,50-/m0/s1
74032-89-6Relevant articles and documents
Synthesis of Peptides by the Solid-Phase Method. 6. Neurotensin, Fragments, and Analogues
St-Pierre, S.,Lalonde, J.-M.,Gendreau, M.,Quirion, R.,Regoli, D.,Rioux, F.
, p. 370 - 376 (2007/10/02)
Neurotensin (NT) and 24 related compounds, including fragments or analogues modified at the C-terminal end of the parent molecule, have been prepared by the solid-phase method.After purification by cation-exchange chromatography, the compounds were characterized by thin-layer chromatography, amino acid analysis, elemental analysis, and high-pressure liquid chromatography.The stimulating effects of the peptides were evaluated in rat stomach strips, in isolated spontaneously beating atria of guinea pigs, and in the coronaries of perfused rat hearts.The differences between the biological activities of these compounds are discussed.
