74071-59-3Relevant articles and documents
Conformationally constrained peptides and semipeptides derived from RGD as potent inhibitors of the platelet fibrinogen receptor and platelet aggregation
Ali,Bennett,Calvo,Elliott,Hwang,Ku,Lago,Nichols,Romoff,Shah,Vasko,Wong,Yellin,Yuan,Samanen
, p. 769 - 780 (2007/10/02)
Structure-activity studies have been pursued on cyclo-S,S-[Ac-Cys-(N(α)- Me)Arg-Gly-Asp-Pen]-NH2, 2 (SK and F 106760), a potent inhibitor of platelet aggregation, in an effort to improve potency and affinity for the GPIIb/IIIa receptor. Modific