741687-06-9

Basic information

• Product Name: N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER
• Synonyms: N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER;1-BOC-4-(PHENYLMETHYL)-4-PIPERIDINECARBOXYLIC ACID METHYL ESTER;1-tert-butyl 4-methyl 4-benzylpiperidine-1,4-dicarboxylate
• CAS NO: 741687-06-9
• Molecular Formula: C₁₉H₂₇NO₄
• Molecular Weight: 333.42198
• Mol File: 741687-06-9.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER(741687-06-9)
• EPA Substance Registry System: N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER(741687-06-9)

Safety Data

• Hazardous Substances Data: 741687-06-9(Hazardous Substances Data)

Upstream product

• 124443-68-1 1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylate 
• 100-39-0 benzyl bromide 
• 67-56-1 methanol 
• 167263-11-8 N-tert-butyloxycarbonyl-4-benzylpiperidine-4-carboxylic acid 

Downstream Products

• 885499-61-6 CCT₁₂₈₉₃₀ 
• 885500-63-0 4-[4-amino-4-(4-chlorobenzyl)-piperidin-1-yl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester 
• 885653-42-9 4-benzylpiperidin-4-amine 
• 885653-43-0 4-(4-chlorobenzyl)-piperidin-4-ylamine 
• 956460-41-6 C₁₇H₂₅ClN₂O₂ 
• 885500-38-9 4-(4-chlorobenzyl)piperidin-4-ylamine dihydrochloride 
• 1057137-22-0 Methyl 4-benzyl-1-[2-(3-nitro-5-trifluoromethylphenoxy)ethyl]piperidine-4-carboxylate 
• 906331-68-8 Methyl 4-benzylpiperidine-4-carboxylate 
• 906329-81-5 methyl 4-phenylmethyl-piperidine-4-carboxylate hydrochloride 
• 741687-09-2 tert-butyl 4-amino-4-benzylpiperidine-1-carboxylate 
• 167263-11-8 N-tert-butyloxycarbonyl-4-benzylpiperidine-4-carboxylic acid 

Relevant articles and documents

Efficient synthesis and identification of novel propane-1,3-diamino bridged CCR5 antagonists with variation on the basic center carrier

By employing pharmacophore-based design and the privileged fragments reassembly, a series of piperidine-/tropane-/piperazine-bridged CCR5 antagonists were designed and synthesized via an efficient convergent synthesis strategy, with focus on the optimal choice of the basic center carrier structure. Significantly, the 4-amino-4-methylpiperidine bridged 1-acyl-1,3-propanediamine compounds were identified as a new class of nanomolar CCR5 antagonists, providing an efficient approach and novel scaffolds for further development of potent CCR5 inhibitors.

ORTHO-CONDENSED PYRIDINE AND PYRIMIDINE DERIVATIVES (E.G. PURINES) AS PROTEIN KINASES INHIBITORS

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Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists

The present invention relates to urotensin II receptor antagonists, pharmaceutical compositions containing them and their use.