74169-52-1

Basic information

• Product Name: Pyrano[2,3-c]pyrazol-6(1H)-one,3,4-dimethyl-1-phenyl-
• Synonyms: Pyrano[2,3-c]pyrazol-6(1H)-one,3,4-dimethyl-1-phenyl-;3,4-dimethyl-1-phenylpyrano[2,3-c]pyrazol-6-one
• CAS NO: 74169-52-1
• Molecular Formula: C₁₄H₁₂N₂O₂
• Molecular Weight: 240.25728
• Mol File: 74169-52-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyrano[2,3-c]pyrazol-6(1H)-one,3,4-dimethyl-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrano[2,3-c]pyrazol-6(1H)-one,3,4-dimethyl-1-phenyl-(74169-52-1)
• EPA Substance Registry System: Pyrano[2,3-c]pyrazol-6(1H)-one,3,4-dimethyl-1-phenyl-(74169-52-1)

Safety Data

• Hazardous Substances Data: 74169-52-1(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 89-25-8 edaravone 
• 626-34-6 ethyl aminocrotonate 
• 141-97-9 ethyl acetoacetate 
• 74529-10-5 N'-phenyl-2-piperidylacetohydrazide 
• 19735-89-8 3-methyl-1-phenylpyrazolin-5(4H)-one 

Downstream Products

• 89-25-8 edaravone 
• 85094-24-2 3,4-Dimethyl-5-nitro-1-(4-nitro-phenyl)-1H-pyrano[2,3-c]pyrazol-6-one 
• 85094-23-1 3,4-Dimethyl-5-nitro-1-phenyl-1H-pyrano[2,3-c]pyrazol-6-one 
• 74169-59-8 5-Bromo-3,4-dimethyl-1-phenyl-1H-pyrano[2,3-c]pyrazol-6-one 
• 85094-37-7 5-Chloro-3,4-dimethyl-1-phenyl-1H-pyrano[2,3-c]pyrazol-6-one 
• 1410076-37-7 7-(2-aminoethyl)-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one 

Relevant articles and documents

Synthesis, pharmacological evaluation and molecular docking of pyranopyrazole-linked 1,4-dihydropyridines as potent positive inotropes

Abstract: 1,4-Dihydropyridines are well-known calcium channel blockers, but variations in the substituents attached to the ring have resulted in their role reversal making them calcium channel activators in some cases. We describe the microwave-assisted e

Facile synthesis of pyrano[2,3-c]pyrazol-6-one derivatives under microwave irradiation in solvent-free conditions

A series of substituted 1H,6H-pyrano[2,3-c]pyrazol-6-one derivatives were synthesized from one-pot cyclocondensation of hydrazine derivatives or 1H-pyrazol-5-one derivatives with various β-keto esters under solvent-free conditions using microwave irradiation in short time with good to excellent yields. Copyright Taylor & Francis LLC.

ETUDE COMPARATIVE DE LA REACTIVITE DE L'ACETOACETATE D'ETHYLE ET DU 3-AMINOCROTONATE D'ETHYLE VIS-A-VIS DE COMPOSES PYRAZOLONIQUES

1-phenyl-3-methylpyrazolin-5-one, 1,5-dimethylpyrazolin-3-one and 1-phenyl-pyrazolidin-3,5-dione react with ethyl acetoacetate to yield pyrano pyrazole-6-ones.Starting from 1-phenyl-3-aminopyrazolin-5-one or from 1-methyl-5-aminopyrazolin-3-one, pyrazolo pyridin-6-ones are obtained.When ethyl 3-aminocrotonate instead of ethyl acetoacetate is used, the course of these reactions remains the same in most cases but yields are always higher.