74275-79-9

Basic information

• Product Name: 2-ethoxy-2-oxoethyl 3-phenylpropanoate
• CAS NO: 74275-79-9
• Molecular Formula: C₁₃H₁₆O₄
• Molecular Weight: 236.2637
• Mol File: 74275-79-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 331.8°C at 760 mmHg
• Flash Point: 161°C
• Density: 1.115g/cm³
• Vapor Pressure: 0.000152mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: 2-ethoxy-2-oxoethyl 3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxy-2-oxoethyl 3-phenylpropanoate(74275-79-9)
• EPA Substance Registry System: 2-ethoxy-2-oxoethyl 3-phenylpropanoate(74275-79-9)

Safety Data

• Hazardous Substances Data: 74275-79-9(Hazardous Substances Data)

Upstream product

• 623-50-7 ethyl 2-hydroxyacetate 
• 645-45-4 hydrocinnamic acid chloride 

Relevant articles and documents

Metal Template Assisted Proximal Arrangement of a Nucleophile and an Electrophile: Site-Selective Acylation of α-Hydroxyamides in Polyols

Site-selective acylation of α-hydroxyl groups in amides has been achieved in the presence of other primary hydroxyl groups with intrinsic high reactivity. In this methodology, a relatively stable pyridine aldoxime ester was exploited as an acyl donor to suppress undesired acylation. The catalytic activation of a pyridine aldoxime ester with a Lewis acid produced a cationic complex, which preferentially attracted the Lewis basic α-hydroxyamide via a template effect, to thus facilitate o-acylation.