74327-27-8Relevant articles and documents
An Ir-photoredox-catalyzed decarboxylative Michael addition of glyoxylic acid acetal as a formyl equivalent
Zhang, Sheng,Tan, Zhoumei,Zhang, Haonan,Liu, Juanli,Xu, Wentao,Xu, Kun
supporting information, p. 11642 - 11645 (2017/11/03)
We reported herein an iridium-photoredox-catalyzed decarboxylative conjugated addition of glyoxylic acid acetals with various Michael acceptors, including unsaturated amide, ester, aldehyde, ketone, and nitrile under irradiation. Vinyl pyridine and α-aryl styrene are also suitable substrates. The reaction offers various types of acetal products, which are of synthetic significance as protected aldehydes.
3,3-Diethoxypropyl-lithium: A Masked Lithium Propanal Homoenolate in Organic Synthesis
Barluenga, Jose,Fernandez, Jose R.,Rubiera, Covadonga,Yus, Miguel
, p. 3113 - 3118 (2007/10/02)
3,3-Diethoxypropyl-lithium is prepared by lithiation of the corresponding chlorinated precursor with lithium naphthalenide at -78 deg C; the reaction of this masked propanal homoenolate with different elctrophilic reagents CO, (CH2)7CO, PhCOMe, PhCH=NPh, PhCONEt2, PhCN, c-C6H11CN, 4-MeC6H4CN> leads to the corresponding mono- and bi-functionalized compounds.In the case of the reaction with aldehydes or ketones the prepared crude products are oxidized with m-chloroperbenzoic acid, yielding directly the γ-substituted butyrolactones.
