74372-90-0Relevant articles and documents
Synthesis and Conformational Analysis of 2-O-Silyl Protected Nucleosides from Unprotected Nucleobases and Sugar Epoxides
Ahmed, Ajaz,Katoch, Meenu,Mukherjee, Debaraj,Rasool, Faheem,Singh, Gurpreet
, (2020/07/21)
Synthesis of orthogonally protected 2-silyl nucleosides were achieved by trans opening of sugar epoxides with nucleobases catalyzed by trimethylsilyltrifluoromethanesulfonate using hexamethyldisilazane both as solvent and silylating agent. Both α and β nu
2-: O-Benzyloxycarbonyl protected glycosyl donors: A revival of carbonate-mediated anchimeric assistance for diastereoselective glycosylation
Weber, Julia,Svatunek, Dennis,Krauter, Simon,Tegl, Gregor,Hametner, Christian,Kosma, Paul,Mikula, Hannes
supporting information, p. 12543 - 12546 (2019/10/28)
By reviving an old idea, we demonstrate that alkoxycarbonyl groups can be used in glycosylation reactions to achieve full stereocontrol through participation of a carbonate moiety at O-2. Various benzyloxycarbonyl-protected glycosyl donors were prepared and used for efficient 1,2-trans glycosylation of base-labile compounds and the synthesis of glycosyl esters.
METHOD FOR PRODUCING GLYCYRRHIZINIC ACID AND GALACTURO GLYCYRRHIZINIC ACID, AND INTERMEDIATE USED FOR THE PRODUCTION METHOD
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Paragraph 0024; 0026, (2018/07/28)
PROBLEM TO BE SOLVED: To provide a synthesis method that makes it possible to produce high-purity glycyrrhizinic acid or galacturo glycyrrhizinic acid, simply and in high yields. SOLUTION: A production method includes performing glycosylation of position-3 hydroxy group of glycyrrhetinic acid, then performing selective galactosylation or glycosylation at position-2', and through deprotection, performing selective oxidation of a primary hydroxy group. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT