74420-50-1

Basic information

• Product Name: 3-METHYL-5-AMINOIMIDAZO[1,2-A]PYRIDINE
• Synonyms: 3-METHYL-5-AMINOIMIDAZO[1,2-A]PYRIDINE;3-Methylimidazo[1,2-a]pyridin-5-amine;5-Amino-3-methylimidazo[1,2-a]pyridine;IMidazo[1,2-a]pyridin-5-aMine, 3-Methyl-;3-Methyl-iMidazo[1,2-a]pyridin-5-ylaMine
• CAS NO: 74420-50-1
• Molecular Formula: C8H9N3
• Molecular Weight: 147.18
• Mol File: 74420-50-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.273g/cm³
• Refractive Index: 1.667
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-METHYL-5-AMINOIMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-5-AMINOIMIDAZO[1,2-A]PYRIDINE(74420-50-1)
• EPA Substance Registry System: 3-METHYL-5-AMINOIMIDAZO[1,2-A]PYRIDINE(74420-50-1)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• WGK Germany: 3
• Hazardous Substances Data: 74420-50-1(Hazardous Substances Data)

Usage

General Description

3-Methyl-5-aminoimidazo[1,2-a]pyridine is a chemical compound with the molecular formula C7H7N3. It is a heterocyclic compound with a ring structure that contains both nitrogen and carbon atoms. This chemical is often used as a building block in the synthesis of pharmaceutical compounds, including anti-cancer and anti-inflammatory drugs. It is also known to have mutagenic and carcinogenic properties, making it a potential health hazard. Therefore, it is important to handle and use this chemical with caution in laboratory and industrial settings.

InChI:InChI=1/C8H9N3/c1-6-5-10-8-4-2-3-7(9)11(6)8/h2-5H,9H2,1H3

Upstream product

• 141-86-6 2.6-diaminopyridine 
• 19967-57-8 bromo-2 propanal 

Downstream Products

• 4926-54-9 3-Methyl-5-bromoimidazo<1,2-a>pyridine 

Relevant articles and documents

Reaction of 3-Substituted Imidazopyridines with Br+ and the Alleged 5-Bromo-Substituted Product

The reaction of 3-methylimidazopyridine with NBS was reinvestigated and is shown to give products formed by apparent nucleophilic substitution at the 2-position.NBS in CHCl3 gave compounds 4 and 6, while NBS in CCl4 or Br2 in CHCl3 gave exclusively 4.Mechanisms and differences in product formation are discussed; evidence that the previously reported NBS product was in fact 3-bromo-5-methylimidazopyridine, rather than the alleged 5-bromo-3-methyl derivative 3, is presented.Compound 3 was prepared by diazotization of 5-amino-3-methylimidazopyridine in the presence of HBr and by condensation of 2-bromopropanal (or its acetal) with 2-amino-6-bromopyridine (12).This latter reaction of the weakly basic aminopyridine 12 is shown to follow the normal pattern in which the amino nitrogen condenses with the carbonyl carbon.Structures are established by infrared, mass, and 1H-NMR spectral analyses, mechanistic considerations, and diagnostic reactions.Experimental and computer-generated 1H-NMR spectra of compounds 3 and 13 are reproduced.