745052-92-0

Basic information

• Product Name: Triphenyl[(tetrahydro-2H-pyran-4-yl)methyl]phosphonium iodide
• Synonyms: Triphenyl[(tetrahydro-2H-pyran-4-yl)methyl]phosphonium iodide;Triphenyl(tetrahydropyran-4-ylmethyl)phosphonium iodide;iodotriphenyl((tetrahydro-2H-pyran-4-yl)methyl)phosphorane;iodotriphenyl((tetrahydro-2H-pyran-4-yl)methyl)-l5-phosphane
• CAS NO: 745052-92-0
• Molecular Formula: C₂₄H₂₆OP*I
• Molecular Weight: 488.340871
• Mol File: 745052-92-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Triphenyl[(tetrahydro-2H-pyran-4-yl)methyl]phosphonium iodide(CAS DataBase Reference)
• NIST Chemistry Reference: Triphenyl[(tetrahydro-2H-pyran-4-yl)methyl]phosphonium iodide(745052-92-0)
• EPA Substance Registry System: Triphenyl[(tetrahydro-2H-pyran-4-yl)methyl]phosphonium iodide(745052-92-0)

Safety Data

• Hazardous Substances Data: 745052-92-0(Hazardous Substances Data)

Usage

General Description

Triphenyl[(tetrahydro-2H-pyran-4-yl)methyl]phosphonium iodide is a chemical compound with the formula (C20H23O)IP. It is a phosphonium salt that contains a tetrahydro-2H-pyran-4-yl)methyl group attached to three phenyl rings and a phosphonium iodide counterion. Triphenyl[(tetrahydro-2H-pyran-4-yl)methyl]phosphonium iodide is commonly used as a phase-transfer catalyst in organic synthesis, particularly in reactions involving nucleophilic substitution and Wittig-type reactions. It functions as a catalyst by facilitating the transfer of reactants between immiscible phases, typically between an aqueous and organic phase, and is known for its ability to enhance reaction rates and yields. Triphenyl[(tetrahydro-2H-pyran-4-yl)methyl]phosphonium iodide is a versatile and valuable chemical tool for synthetic chemists.

Upstream product

• 101691-94-5 4-(iodomethyl)tetrahydro-2H-pyran 
• 603-35-0 triphenylphosphine 
• 101691-65-0 toluene-4-sulfonic acid tetrahydropyran-4-ylmethyl ester 
• 14774-37-9 (tetrahydro-2H-pyran-4-yl)methanol 

Downstream Products

• 1174229-16-3 ethyl 2-[3-bromo-4-(cyclopropylsulfanyl)phenyl]-3-(tetrahydro-2H-pyran-4-yl)acrylate 
• 745052-96-4 ethyl 2-(4-(cyclopropylsulfonyl)phenyl)-3-(tetrahydro-2H-pyran-4-yl)acrylate 
• 745052-95-3 ethyl 2-(4-(cyclopropylthio)phenyl)-3-(tetrahydro-2H-pyran-4-yl)acrylate 
• 745052-98-6 (E)-2-(4-(cyclopropylsulfonyl)phenyl)-3-(tetrahydro-2H-pyran-4-yl)acrylic acid 
• 1397795-19-5 (E)-ethyl 2-(4-(cyclopropylthio)phenyl)-3-(tetrahydro-2H-pyran-4-yl)acrylate 
• 1397795-26-4 (Z)-ethyl 2-(4-(cyclopropylthio)phenyl)-3-(tetrahydro-2H-pyran-4-yl)acrylate 

Relevant articles and documents

CONDENSED RING HETEROCYCLIC COMPOUND

The ring-fused heterocyclic compound or a pharmaceutically acceptable salt thereof according to the present invention has a T-type calcium channel regulatory effect, and is useful, for example, as a medicament for treating and/or preventing pruritus. The present invention provides a ring-fused heterocyclic compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof and the like which has a T-type calcium channel regulatory effect and is useful as a therapeutic and/or preventive agent for pruritus, and the like. [wherein, R1 represents optionally substituted lower alkyl and the like, R2 represents optionally substituted lower alkyl and the like, R3 represents the formula (II): (wherein, n represents 0 or 1, R3a represents a hydrogen atom and the like, R3b represents a hydrogen atom and the like, and R3c represents a hydrogen atom and the like) and the like, Q represents a hydrogen atom and the like, and W1 represents a nitrogen atom and the like, W2 represents a nitrogen atom and the like]

TRICYCLO SUBSTITUTED AMIDES

Compounds of Formula (I) or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.

FLUORINATION PROCESS OF PROTECTED AMINOTHIAZOLE

A process for the production of fluorinated compound formula (I) comprising fluorination of a protected aminothiazole. Compounds formula (I) are useful in the preparation of activators of glucokinase.