7456-83-9Relevant articles and documents
4-SUBSTITUTED PYRANO[3,4,B]PYRAZINE KAPPA AGONISTS FOR TREATING DRUG DEPENDENCY
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Paragraph 045; 047, (2020/12/29)
1-Phenylacetyl-8-aminohexahydro-2H-pyrano[3,4-b]pyrazines of formula I are disclosed. The compounds are kappa ligands and are useful to treat drug dependency.
PYRANO[3,4-B]PYRAZINE KAPPA OPIOID RECEPTOR LIGANDS FOR TREATING ADDICTION, PRURITUS, PAIN, AND INFLAMMATION
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Paragraph 059, (2019/06/23)
l-Phenylacetyl-8-aminohexahydro-2H-pyrano[3,4-b]pyrazines of formula Formula (I) are disclosed. The compounds are kappa ligands and are useful to treat drug dependency, pruritus, pain, and inflammation.
SUBSTITUTED BRIDGED DIAZEPANE DERIVATIVES AND USE THEREOF
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Page/Page column 64, (2019/01/07)
The present application relates to novel imidazopyridinyl-or imidazopyrimidinyl-substituted, bridged 1,4-diazepane derivatives, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of respiratory disorders including, sleep-related respiratory disorders such as obstructive sleep apnoeas and central sleep apnoeas and snoring.