7473-38-3

Basic information

• Product Name: BENZYL BETA-L-ARABINOPYRANOSIDE
• Synonyms: Nsc400277;Benzyl-β-L-Arabinoside;BENZYL BETA-L-ARABINOPYRANOSIDE
• CAS NO: 7473-38-3
• Molecular Formula: C₁₂H₁₆O₅
• Molecular Weight: 240.25
• Mol File: 7473-38-3.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 418.5°Cat760mmHg
• Flash Point: 206.9°C
• Appearance: /
• Density: 1.35g/cm³
• CAS DataBase Reference: BENZYL BETA-L-ARABINOPYRANOSIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL BETA-L-ARABINOPYRANOSIDE(7473-38-3)
• EPA Substance Registry System: BENZYL BETA-L-ARABINOPYRANOSIDE(7473-38-3)

Safety Data

• Hazardous Substances Data: 7473-38-3(Hazardous Substances Data)

Usage

General Description

Benzyl beta-L-arabinopyranoside is a natural chemical compound found in several plant sources including fruits and vegetables. It is a form of arabinopyranoside, a type of sugar molecule. BENZYL BETA-L-ARABINOPYRANOSIDE has been studied for its potential therapeutic effects, including its anti-cancer and anti-inflammatory properties. Benzyl beta-L-arabinopyranoside has also been researched for its antimicrobial activity and has shown promise as a potential ingredient in pharmaceutical and cosmetic products. As a natural product, it has gained attention for its potential health benefits and is being further investigated for its various biological activities.

Upstream product

• 87-72-9 L-(+)-arabinose 
• 100-51-6 benzyl alcohol 
• 7296-55-1 L-arabinose 
• 7296-56-2 β-L-arabinopyranose 
• 7553-56-2 iodine 
• 18403-22-0 (3aS,6S,7R,7aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol 
• 3068-31-3 1-bromo-2,3,4-tri-O-acetyl-α-D-xylopyranose 
• 1114-34-7 D-lyxose 
• 5328-37-0 L-arabinose 
• 87-72-9 L-arabinofuranose 

Downstream Products

• 145075-81-6 3β,16β,17α-trihydroxycholest-5-en-22-one 16-O-{O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-(1->3)-2-O-acetyl-β-L-arabinopyranoside} 
• 219906-54-4 4-Methoxy-benzoic acid (2S,3R,4R,5R)-2-((3S,4S,5R,6S)-5-acetoxy-6-benzyloxy-4-hydroxy-tetrahydro-pyran-3-yloxy)-4,5-bis-triethylsilanyloxy-tetrahydro-pyran-3-yl ester 
• 219906-53-3 4-Methoxy-benzoic acid (2S,3R,4R,5R)-2-((2S,3R,4S,5S)-3-acetoxy-2-benzyloxy-5-hydroxy-tetrahydro-pyran-4-yloxy)-4,5-bis-triethylsilanyloxy-tetrahydro-pyran-3-yl ester 
• 219906-55-5 4-Methoxy-benzoic acid (2S,3R,4R,5R)-2-((2S,3R,4R,5S)-3-acetoxy-2-benzyloxy-5-triethylsilanyloxy-tetrahydro-pyran-4-yloxy)-4,5-bis-triethylsilanyloxy-tetrahydro-pyran-3-yl ester 
• 321125-08-0 2-O-(4-methoxybenzoyl)-3,4-di-O-triethylsilyl-β-D-xylopyranosyl-(1→3)-2-O-acetyl-4-O-triethylsilyl-α,β-L-arabinopyranosyl trichloroacetimidate 
• 219906-58-8 C₇₃H₁₂₈O₁₆Si₄ 
• 7494-97-5 benzyl 2,3,4-tri-O-benzyl-β-L-arabinopyranoside 
• 1170680-42-8 C₂₀H₂₈O₇ 
• 81692-03-7 benzyl exo-3,4-O-benzylidene-2-O-(p-toluenesulfonyl)-β-L-arabinopyranoside 
• 81704-66-7 benzyl endo-3,4-O-benzylidene-2-O-(p-toluenesulfonyl)-β-L-arabinopyranoside 
• 81691-99-8 benzyl 2-O-benzyl-exo-3,4-O-benzylidene-β-L-arabinopyranoside 
• 81692-00-4 benzyl 2-O-benzyl-endo-3,4-O-benzylidene-β-L-arabinopyranoside 
• 79936-19-9 benzyl 2,4-di-O-benzyl-β-L-arabinopyranoside 
• 73683-78-0 benzyl 2,3-di-O-benzyl-β-L-arabinopyranoside 

Relevant articles and documents

BIARYL AMIDES WITH MODIFIED SUGAR GROUPS FOR TREATMENT OF DISEASES ASSOCIATED WITH HEAT SHOCK PROTEIN PATHWAY

Provided are biaryl amides and coumarin-based compounds with modified sugar groups for treatment of diseases associated with heat shock protein pathway. The compounds having the following formulas, wherein variables are as defined herein. Formulae (I), (II), (III), (IV), and (V), Pharmaceutical compositions of the compounds are also provided. These biaryl amides and coumarin-based derivatives with modified sugar groups are useful for treatment and prevention of diseases and disorders, including neurological disorders, such as neurodegenerative diseases and nerve damaging disorders, for example, diabetic peripheral neuropathy.

Synthesis and inhibition properties of a series of pyranose derivatives towards a Zn-metalloproteinase from Saccharomonospora canescens

The Zn-proteinase, isolated from Saccharomonospora canescens (NPS), shares many common features with thermolysin, but considerable differences are also evident, as far as the substrate recognition site is concerned. In substrates of general structure AcylAlaAlaPhe 4NA, this neutral proteinase cleaves only the arylamide bond (non-typical activity of Zn-proteinases), while thermolysin attacks the peptide bond Ala-Phe. Phosphoramidon is a powerful tight binding inhibitor for thermolysin and significantly less specific towards NPS. The Ki-values (65 μM for NPS vs 0.034 μM for thermolysin) differ nearly 2000-folds. This implies significant differences in the specificity of the corresponding subsites. The carbohydrate moiety is supposed to accommodate in the S1-subsite and the series of arabinopyranosides and glucopyranosides (12 compounds), which are assayed as inhibitors in a model system: NPS with SucAlaAlaPhe4NA as a substrate could be considered as mapping the S1-subsite of NPS. Members of the series with an additional ring (3,4-epithio, 3,4-anhydro-derivatives) turned out to be reasonably good competitive inhibitors (Ki ≈ 0.1-0.2 mM are of the same order as the Ki value for phosphoramidon). The structure of these compounds (8, 9, 11 and 12) seems to fit the size of the S1-subsite and due to an appropriately oriented OH-group in addition, to protect the active site Zn2+.

Synthesis of 6- and 7-(1,2,3-trihydroxy-1,2-O-isopropyl-denepropyl)pteridines and deoxygenation of their 3′-hydroxy groups

Treatment of 3,4-O-isopropylidene-L-threo-pentos-2-ulose (7) with 5,6-diamino-1,3-dimethyluracil (8) afforded 1,3-dimethyl-6-[(1R,2S)-1,2,3-trihydroxy-1,2-O-isopropylidenepropyl]lumazine (9a) and its 7-substituted isomer (9b). Deoxygenation of 3′-hydroxy