7482-91-9

Basic information

• Product Name: 2-PYRIDIN-3-YL-QUINOLINE-4-CARBOXYLIC ACID
• Synonyms: AKOS BBS-00000319;2-PYRIDIN-3-YL-QUINOLINE-4-CARBOXYLIC ACID;IFLAB-BB F0307-0468;TIMTEC-BB SBB000895;2-pyridin-3-ylquinoline-4-carboxylic acid(SALTDATA: FREE);2-(3-pyridyl)-4-quinolinecarboxylic acid;2-(3-Pyridyl)cinchoninic acid;2-(3-Pyridyl)cinchoninsaeure [German]
• CAS NO: 7482-91-9
• Molecular Formula: C₁₅H₁₀N₂O₂
• Molecular Weight: 250.25
• Mol File: 7482-91-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 290 °C(Solv: methanol (67-56-1); ethanol (64-17-5))
• Boiling Point: 481.9 °C at 760 mmHg
• Flash Point: 245.2 °C
• Appearance: /
• Density: 1.332 g/cm³
• Vapor Pressure: 4.27E-10mmHg at 25°C
• Refractive Index: 1.69
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.02±0.10(Predicted)
• CAS DataBase Reference: 2-PYRIDIN-3-YL-QUINOLINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PYRIDIN-3-YL-QUINOLINE-4-CARBOXYLIC ACID(7482-91-9)
• EPA Substance Registry System: 2-PYRIDIN-3-YL-QUINOLINE-4-CARBOXYLIC ACID(7482-91-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 7482-91-9(Hazardous Substances Data)

Usage

General Description

2-Pyridin-3-yl-quinoline-4-carboxylic acid is a compound that is derived from both pyridine and quinoline. Its molecular structure consists of a quinoline ring, a type of heterocyclic aromatic organic compound, attached to a pyridine ring, another type of aromatic heterocycle, by a single bond. At the 4-position of the quinoline ring, there is a carboxylic acid group. 2-PYRIDIN-3-YL-QUINOLINE-4-CARBOXYLIC ACID is mainly characterized by its extensive conjugation and aromaticity, considering both of its rings are aromatic. The presence of the carboxylic acid group can render it polar and capable of participating in hydrogen bonding, which can significantly influence its properties. Its applications or properties are not widely reported in the literature, indicating that it might be a substance primarily used for research purposes.

InChI:InChI=1/C15H10N2O2/c18-15(19)12-8-14(10-4-3-7-16-9-10)17-13-6-2-1-5-11(12)13/h1-9H,(H,18,19)

Upstream product

• 350-03-8 methyl-3-pyridylketone 
• 91-56-5 indole-2,3-dione 
• 101714-03-8 2-oxo-4-(3-pyridyl)-3-butene-1-oic acid 
• 62-53-3 aniline 

Downstream Products

• 6294-65-1 2-pyridin-3-yl-quinoline 

Relevant articles and documents

Design of a dual sensing highly selective cyanide chemodosimeter based on pyridinium ring chemistry

A new chemodosimeter, Quino-P, recognizes the strongly nucleophilic cyanide by dual colorimetric and fluorescence 'off-on' signalling responses. Noteworthily, several other anions, even in significantly higher concentrations, induce no detectable photophysical perturbations. The chemodosimeter mechanism involves formation of a C4-cyano adduct, which exhibits an uncommon phenomenon of enhanced internal charge transfer interaction. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2011.

Discovery of Potent Small-Molecule SIRT6 Activators: Structure-Activity Relationship and Anti-Pancreatic Ductal Adenocarcinoma Activity

SIRT6 activation is thought to be a promising target for the treatment of many diseases, particularly cancer. Herein, we report the discovery of a series of new small-molecule SIRT6 activators. Structure-activity relationship analyses led to the identific

Cytochrome P450 2C9 type II binding studies on quinoline-4-carboxamide analogues

CYP2C9 is a significant P450 protein responsible for drug metabolism. With the increased use of heterocyclic compounds in drug design, a rapid and efficient predrug screening of these potential type II binding compounds is essential to avoid adverse drug