749240-52-6

Basic information

• Product Name: 4,7-DIFLUOROISATIN
• Synonyms: 4,7-DIFLUOROISATIN;4,7-DIFLUOROINDOLINE-2,3-DIONE;UKRORGSYN-BB BBV-037169;4,7-Difluoro indole-2,3-dione
• CAS NO: 749240-52-6
• Molecular Formula: C₈H₃F₂NO₂
• Molecular Weight: 183.11
• Product Categories: Indole/indoline/oxindole;Indoles and derivatives
• Mol File: 749240-52-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Density: 1.578±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.24±0.20(Predicted)
• CAS DataBase Reference: 4,7-DIFLUOROISATIN(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7-DIFLUOROISATIN(749240-52-6)
• EPA Substance Registry System: 4,7-DIFLUOROISATIN(749240-52-6)

Safety Data

• Hazardous Substances Data: 749240-52-6(Hazardous Substances Data)

Usage

General Description

4,7-Difluoroisatin is a chemical compound with the molecular formula C8H4F2N2O2. It is a derivative of isatin, a heterocyclic compound that is used in the synthesis of various pharmaceuticals and agrochemicals. 4,7-Difluoroisatin is a yellow-orange crystalline solid that is insoluble in water but soluble in organic solvents. It is primarily used as a building block in the synthesis of heterocyclic compounds and as a precursor in organic reactions. 4,7-Difluoroisatin has potential applications in the pharmaceutical and agricultural industries, making it a valuable intermediate in organic synthesis. Its unique chemical structure and properties make it a versatile and important chemical in the field of organic chemistry.

Upstream product

• 367-30-6 2,5-difluoroaniline 
• 75-87-6 chloral 
• 850565-99-0 N-(2,5-difluorophenyl)-2-(hydroxyimino)acetamide 
• 825654-53-3 5-amino-8-fluoro-2-methyl-quinazoline 

Downstream Products

• 825654-54-4 2-amino-3,6-difluorobenzoic acid 

Relevant articles and documents

Reductive ring closure methodology toward heteroacenes bearing a dihydropyrrolo[3,2- B ]pyrrole core: Scope and limitation

A newly developed reductive ring closure methodology to heteroacenes bearing a dihydropyrrolo[3,2-b]pyrrole core was systematically studied for its scope and limitation. The methodology involves (i) the cyclization of an o-aminobenzoic acid ester derivative to give an eight-membered cyclic dilactam, and (ii) the conversion of the dilactams into the corresponding diimidoyl chloride, which undergoes (iii) reductive ring closure to install the dihydropyrrolo[3,2-b]pyrrole core. The first step of the methodology plays the key role due to its substrate limitation, which suffers from the competition of oligomerization and hydrolysis. All the dilactams could successfully convert to the corresponding diimidoyl chlorides, most of which succeeded to give the dihydropyrrolo[3,2-b]pyrrole core. The influence of the substituents and the elongation of conjugated length on the photophysical properties of the obtained heteroacenes were then investigated systematically using UV-vis spectroscopy and cyclic voltammetry. It was found that chlorination and fluorination had quite a different effect on the photophysical properties of the heteroacene, and the ring fusing pattern also had a drastic influence on the band gap of the heteroacene. The successful preparation of a series of heteroacenes bearing a dihydropyrrolo[3,2-b]pyrrole core would provide a wide variety of candidates for further fabrication of organic field-effect transistor devices.

TETRAHYDRONAPHTHALENE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS

The invention relates to tetrahydronaphthalene derivatives of general formula (I), to a method for their production and to their use as anti-inflammatory agents.

HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS

The invention relates to pentanol derivatives of general formula (I), which are substituted by quinazoline, quinoxaline, cinnoline, indazole, phthalazine, naphthyridine, benzothiazole, dihydroindolone, dihydroisoindolone, benzimidazole, or indole, a method for the production thereof, and the use thereof as anti-inflammatory agents.