75007-99-7Relevant articles and documents
Design and synthesis of imidazo[4,5-c]pyridine derivatives as promising Aurora kinase A (AURKA) inhibitors
Lomov,Lyashchuk,Abramyants
, p. 1822 - 1829 (2016)
Computer simulation at the PM7 level of theory of the structures of imidazo[4,5-c]pyridine derivatives (deaza analogs of purines) and their complexes with Aurora kinase A (AURKA) indicated prospects for their use as potential AURKA inhibitors in the treatment of oncological diseases. A number of new compounds of the selected imidazo[4,5-c]pyridine series, for which the highest inhibitory activity against AURKA was predicted, were synthesized in high yields for further biological testing.
Synthesis of imidazo[4,5 b]- and [4,5 c]pyridines
Middleton,Wibberley
, p. 1757 - 1760 (2007/10/02)
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