75258-85-4

Basic information

• Product Name: 2-p-Methoxybenzylidene-5-methoxy-1-indanone
• Synonyms: 2-p-Methoxybenzylidene-5-methoxy-1-indanone
• CAS NO: 75258-85-4
• Molecular Weight: 280.323
• Mol File: 75258-85-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-p-Methoxybenzylidene-5-methoxy-1-indanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-p-Methoxybenzylidene-5-methoxy-1-indanone(75258-85-4)
• EPA Substance Registry System: 2-p-Methoxybenzylidene-5-methoxy-1-indanone(75258-85-4)

Safety Data

• Hazardous Substances Data: 75258-85-4(Hazardous Substances Data)

Upstream product

• 5111-70-6 5-methoxy-1-indanone 
• 123-11-5 4-methoxy-benzaldehyde 
• 5111-69-3 5-methoxyindane 

Relevant articles and documents

Syntheses of 2-methoxyestradiol and eugenol template based diarylpropenes as non-steroidal anticancer agents

Syntheses of 2-methoxyestradiol (1) and eugenol (6) template based conformationally flexible and rigid diarylpropenes, 14(a-l) and 20(a-e), as nonsteroidal anticancer agents have been performed. The synthesized compounds were evaluated for their anticance

Studies in Antifertility Agents: Part XXV - 2-Carboxy-7-hydroxy-1-phenyl-1,2,3,4-tetrahydrofluorene

The synthesis and stereochemical assignments of 2-carboxy-7-hydroxy-1-phenyl-1,2,3,4-tetrahydrofluorene (17) are reported. 2-Arylidene-5-methoxy-1-indanones (5-8) have been prepared by condensation of 5-methoxy-1-indanone (1) with araldehydes (2-4).Addition of methyl acetoacetate onto 5 furnishes 2-carbomethoxy-7-methoxy-3-oxo-1-phenyl-1,2,3,9a-tetrahydrofluorene (9), which under acid hydrolysis gives the enone (10), and on treatment with ethanedithiol affords the thioketal (11).Desulphurization of 11 with Raney nickel yields 1,2-trans-2-carbomethoxy-7-methoxy-1-phenyl-1,2,3,4-tetrahydrofluorene (12).Catalytic hydrogenation of 12 affords possibly B/C-cis-1,2-trans-1,2,3,4,4a,9a-hexahydrofluorene (13).Alkaline hydrolysis of esters 11, 12 and 13 gives the corresponding acids 15, 16 and 14.Demethylation of 16 with BBr3-CH2Cl2 furnishes the title hydroxy acid (17).None of these compounds prevents pregnancy at a dose of 10 mg/kg in rats.