7529-24-0

Basic information

• Product Name: 1H-Phosphole, 1-ethyl-2,5-dihydro-3-methyl-, 1-oxide
• Synonyms: 1-ethyl-3-methyl-3-phospholene 1-oxide;1-ethyl-3-methyl-2,5-dihydro-1H-phosphole oxide;1-ethyl-3-methyl-2,5-dihydro-1H-phosphole 1-oxide;1-ethyl-3-methyl-3-phospholene oxide;1-Aethyl-3-methyl-2,5-dihydro-1H-phosphol-1-oxid;1-oxo-1-ethyl-3-methylphosphol-3-ene;1H-Phosphole,1-ethyl-2,5-dihydro-3-methyl-,1-oxide
• CAS NO: 7529-24-0
• Molecular Formula: C7H13OP
• Molecular Weight: 144.15100
• Mol File: 7529-24-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Phosphole, 1-ethyl-2,5-dihydro-3-methyl-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Phosphole, 1-ethyl-2,5-dihydro-3-methyl-, 1-oxide(7529-24-0)
• EPA Substance Registry System: 1H-Phosphole, 1-ethyl-2,5-dihydro-3-methyl-, 1-oxide(7529-24-0)

Safety Data

• Hazardous Substances Data: 7529-24-0(Hazardous Substances Data)

Usage

Chemical Family

1H-Phosphole, 1-ethyl-2,5-dihydro-3-methyl-, 1-oxide belongs to the phosphole oxide family.

Molecular Weight

The molecular weight of the compound is 148.15 g/mol.

Structure

The compound is a phosphorus-containing heterocyclic compound, featuring a five-membered ring with one phosphorus atom and four carbon atoms.

Application in Organic Synthesis

1H-Phosphole, 1-ethyl-2,5-dihydro-3-methyl-, 1-oxide is used in organic synthesis due to its unique structure and properties.

Pharmaceutical Research

The compound is also utilized in pharmaceutical research, potentially leading to the development of new drugs and therapies.

Material Production

It is used in the production of materials such as polymers and adhesives, showcasing its versatility in various chemical and industrial applications.

Upstream product

• 87243-93-4 1-hydroxy-3-methyl-3-phospholene 1-oxide 
• 925-90-6 ethylmagnesium bromide 
• 18874-22-1 1-chloro-3-methyl-3-phospholene-1-oxide 
• 74-96-4 ethyl bromide 
• 50982-88-2 1-(2-chloroethoxy)-3-methylphosphol-3-ene 
• 67-56-1 methanol 

Relevant articles and documents

Platinum(II) complexes incorporating racemic and optically active 1-alkyl-3-phospholene P-ligands: Synthesis, stereostructure, NMR properties and catalytic activity

Three 1-alkyl-3-phospholene 1-oxides, such as the P-ethyl, P-isobutyl and P-isopentyl derivative were prepared in racemic and enantiopure forms. After deoxygenation, the cyclic phosphines were converted to the corresponding phosphineeboranes and phosphine

Process

A process is described for the preparation of phospholene-1-oxides and 1-sulfides having an aliphatic substituent in the 1-position, a double bond at the 2- or 3-positions and, optionally, having additional substituents at one or more of positions 2, 3, 4 or 5. The process comprises the reaction of a 1-(2-chloroalkoxy)-phospholene with the appropriate aliphatic alcohol or thiol optionally in the presence of an alkylation catalyst. Use of an aliphatic alcohol gives rise to a phospholene oxide while use of the corresponding thiol gives rise to a phospholene sulfide. The phospholene-1-oxides and 1-sulfides so obtained are useful as catalysts for the conversion of isocyanates to carbodiimides.