75333-84-5Relevant articles and documents
Lipophilic and hydrophilic esters of 4-acetyl-2-(2-hydroxyethyl)-5,6-bis (4-chlorophenyl)2h-pyridazin-3-one as antihypertensive agents
Fogt,Scozzie,Heilman,Powers
, p. 1445 - 1448 (2007/10/02)
In an attempt to enhance the antihypertensive activity of 4-acetyl-2-(2-hydroxyethyl)-5,6-bis(4-chlorophenyl)-2H-pyridazin-3-one, (1), a series of lipophilic and hydrophilic esters was synthesized. These derivatives possessed increased lipid and aqueous s