75640-69-6 Usage
General Description
(R)-3,3'-DIBROMO-2,2'-DIMETHOXY-1,1'-BINAPHTHYL is a chemical compound that is commonly used as a chiral ligand and a catalyst in asymmetric synthesis. It belongs to the binaphthyl family of compounds and features two bromine atoms and two methoxy groups attached to a central binaphthyl unit. (R)-3,3'-DIBROMO-2,2'-DIMETHOXY-1,1'-BINAPHTHYL is known for its ability to catalyze various asymmetric reactions, particularly in the fields of organic chemistry and pharmaceutical research. Its unique stereochemistry and 3D arrangement make it a versatile tool for producing enantiomerically pure compounds, which is important in the development of pharmaceuticals and fine chemicals. Additionally, its electron-rich nature and steric properties make it an effective chiral ligand in various transition metal catalyzed reactions. Overall, (R)-3,3'-DIBROMO-2,2'-DIMETHOXY-1,1'-BINAPHTHYL plays a crucial role in the advancement of asymmetric synthesis and the production of chiral molecules with high optical purity.
Check Digit Verification of cas no
The CAS Registry Mumber 75640-69-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,6,4 and 0 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 75640-69:
(7*7)+(6*5)+(5*6)+(4*4)+(3*0)+(2*6)+(1*9)=146
146 % 10 = 6
So 75640-69-6 is a valid CAS Registry Number.
75640-69-6Relevant articles and documents
Oxidation of BINOLs by Hypervalent Iodine Reagents: Facile Synthesis of Xanthenes and Lactones
Wirth, Thomas,Zhang, Huaiyuan
supporting information, (2022/03/17)
Xanthene derivatives have broad applications in medicines, fluorescent probes, dyes, food additives, etc. Therefore, much attention was focused on developing the synthetic methods to prepare these compounds. Binaphthyl-based xanthene derivatives were prepared through the oxidation of BINOLs promoted by the hypervalent iodine reagent iodosylbenzene (PhIO). Nine-membered lactones were obtained through a similar oxidative reaction when iodoxybenzene (PhIO2) was used. Additionally, one-pot reactions of BINOLs, PhIO and nucleophiles such as alcohols and amines were also investigated to provide alkoxylated products and amides in good to excellent yields.
Host-Guest Complexation. 23. High Chiral Recognition of Amino Acid and Ester Guests by Hosts Containing One Chiral Element
Lingenfelter, David S.,Helgeson, Roger C.,Cram, Donald J.
, p. 393 - 406 (2007/10/02)
The chiral recognition properties of ten enantiomerically pure hosts toward the enantiomers of six different amino acids and their methyl esters have been examined.The hosts possessed the general structure (A)2D(OEOEO)2E, in which D is the chiral 1,1'-din
