75738-58-8

Basic information

• Product Name: Cefmenoxime hydrochloride
• Synonyms: 8-[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino-4-[(1-methyltetrazol-5-yl)sulfanylmethyl]-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid hydrochloride (2:1);CEFMENOXIME HCL;CEFMENOXIME HYDROCHLORIDE;)(methoxyimino)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-ox;ab50912hemihydrochloride;cefmenoximehemihydrochloride;hydrochloride(2:1),(6r-(6-alpha,7-beta(z)))-o;sce1365hydrochloride
• CAS NO: 75738-58-8
• Molecular Formula: C32H35ClN18O10S6
• Molecular Weight: 1059.58
• EINECS: 278-299-4
• Product Categories: Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;CEFMAX
• Mol File: 75738-58-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: DMSO (Slightly, Heated), Methanol (Slightly)
• CAS DataBase Reference: Cefmenoxime hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Cefmenoxime hydrochloride(75738-58-8)
• EPA Substance Registry System: Cefmenoxime hydrochloride(75738-58-8)

Safety Data

• Hazardous Substances Data: 75738-58-8(Hazardous Substances Data)

Usage

Description

Cef menoxime hydrochloride is a third generation cephalosporin antibiotic. Structurally, it possesses the (1-methyl-lH-tetrazol-5-yl)thiomethyl moiety in the 3-position; like several other compounds containing this structural element (moxalactam, cefoperazone, cefamandol), bleeding linked to vitamin K interaction has been reported. Cefmenoxime has activity similar to cefotiuime, ceftizoxime and moxalactam against E.coli, C. diversus, Klebsiella, P. Mirabilis, Salmonella, Shigella, Neiseria spp., S. pyogenes, S. Pneumoniae, and g. influenzae. It is relatively ineffective against Pseudomonas and Bacteroidea.

Originator

Takeda (Japan)

Uses

Different sources of media describe the Uses of 75738-58-8 differently. You can refer to the following data:
1. A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis.
2. antibacterial

Definition

ChEBI: The hemihydrochloride salt of cefmenoxime.

Brand name

Cefmax (TAP);TACEF;BESTCALL.

InChI:InChI=1/2C16H17N9O5S3.ClH/c2*1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7;/h2*5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29);1H/b2*21-8-;/t2*9-,13-;/m11./s1