75748-50-4 Usage
Originator
Ancarolol,ZYF Pharm Chemical
Manufacturing Process
A mixture of 23 g of 2'-(2,3-epoxypropoxy)-furan-2-carboxylic acid anilide,
7.3 g of t-butylamine and 50 ml of isopropanol is boiled under reflux for 10
hours. On cooling, 2'-(2-hydroxy-3-t-butylaminopropoxy)-furan-2-carboxylic
acid anilide (ancarolol) crystallizes out from the solution. The
chromatographically pure base is obtained in the form of a white solid of
melting point 112°-113°C by recrystallization from ethyl acetate. The yield is
12 g. The colorless, crystalline base is dissolved in alcohol, alcoholic HCl is
added and the hydrochloride is induced to crystallize by adding ether
dropwise. After isolation, the salt is recrystallized again from ethanol. This
gives 10 g of the hydrochloride, melting point 189°-191°C.
Therapeutic Function
Beta-adrenergic blocker
Check Digit Verification of cas no
The CAS Registry Mumber 75748-50-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,4 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 75748-50:
(7*7)+(6*5)+(5*7)+(4*4)+(3*8)+(2*5)+(1*0)=164
164 % 10 = 4
So 75748-50-4 is a valid CAS Registry Number.
InChI:InChI=1/C18H24N2O4/c1-18(2,3)19-11-13(21)12-24-15-8-5-4-7-14(15)20-17(22)16-9-6-10-23-16/h4-10,13,19,21H,11-12H2,1-3H3,(H,20,22)
