757976-21-9

Basic information

• Product Name: 1,2-Propanediamine,N1-(4-methoxyphenyl)-,(2S)-(9CI)
• Synonyms: 1,2-Propanediamine,N1-(4-methoxyphenyl)-,(2S)-(9CI)
• CAS NO: 757976-21-9
• Molecular Formula: C₁₀H₁₆N₂O
• Molecular Weight: 0
• Product Categories: METHOXY
• Mol File: 757976-21-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-Propanediamine,N1-(4-methoxyphenyl)-,(2S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Propanediamine,N1-(4-methoxyphenyl)-,(2S)-(9CI)(757976-21-9)
• EPA Substance Registry System: 1,2-Propanediamine,N1-(4-methoxyphenyl)-,(2S)-(9CI)(757976-21-9)

Safety Data

• Hazardous Substances Data: 757976-21-9(Hazardous Substances Data)

Usage

Molecular weight

165.23 g/mol The mass of one mole of the compound, calculated from its molecular formula.

Organic compound

It is a carbon-based compound, which is typical for organic chemistry.

Applications

Pharmaceutical manufacturing, agrochemical production, and specialty chemicals The compound is used as a building block in the synthesis of various compounds, including anticancer agents and anti-inflammatory drugs.

Use in drug discovery and research

The compound is commonly used in the development of new chemical entities for various therapeutic purposes.

Chiral compound

As a chiral compound, it is important in the field of drug discovery and development, as it can be used to produce enantiomerically pure drugs with potentially improved pharmacological properties.

Upstream product

• 757976-18-4 tert-butyl {(1S)-2-[(4-methoxyphenyl)amino]-1-methylethyl}carbamate 
• 76-05-1 trifluoroacetic acid 
• 104-94-9 4-methoxy-aniline 
• 63228-64-8 N-(4'-methoxyphenyl)-2-nitrobenzenesulfonamide 

Relevant articles and documents

4-Aminophenoxyacetic acids as a novel class of reversible cathepsin K inhibitors

We have designed and synthesized a novel series of 3-biphenylamino acid amides as cathepsin K inhibitors based on compound I. In these inhibitors, we have discovered 4-aminophenoxyacetic acids 43 and 47 with good IC50 values, although lipophili

Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: Heterocyclic P3

A series of Nα-2-benzoxazolyl-α-amino acid-(arylaminoethyl)amides were identified as potent, selective, and noncovalent inhibitors of cathepsin S. Structure-activity relationships including strategies for modulating the selectivities among cathepsins S, K, and L, and in vivo pharmacokinetics are discussed. A X-ray structure of compound 3 bound to the active site of cathepsin S is also reported.