758-42-9

Basic information

• Product Name: 1,1,1-TRICHLOROTRIFLUOROACETONE
• Synonyms: 1,1,1-trichloro-3,3,3-trifluoroacetone;1,1,1-Trichlorotrifluoroacetone 97%;1,1,1-Trichlorotrifluoroacetone97%;1,1,1-Trifluoro-3,3,3-trichlorpropan-2-one;1,1,1-Trichloro-3,3,3-trifluoro-2-propanone;2,4,6-Trichlorothiophenol;1,1,1-Trichloro-3,3,3-trifluoroacetone 97%;1,1,1-Trichloro-3,3,3-trifluoropropan-2-one, 2-Oxo-1,1,1-trichloro-3,3,3-trifluoropropane
• CAS NO: 758-42-9
• Molecular Formula: C₃Cl₃F₃O
• Molecular Weight: 215.39
• EINECS: 212-063-3
• Mol File: 758-42-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 86 °C
• Flash Point: 87.2 °C
• Appearance: /
• Density: 1,6 g/cm3
• Vapor Pressure: 1.46mmHg at 25°C
• Refractive Index: 1.381
• CAS DataBase Reference: 1,1,1-TRICHLOROTRIFLUOROACETONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-TRICHLOROTRIFLUOROACETONE(758-42-9)
• EPA Substance Registry System: 1,1,1-TRICHLOROTRIFLUOROACETONE(758-42-9)

Safety Data

• Hazard Codes: C
• Statements: 34-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 3265
• HazardClass: CORROSIVE
• Hazardous Substances Data: 758-42-9(Hazardous Substances Data)

Usage

General Description

1,1,1-Trichlorotrifluoroacetone, also known as trifluoroacetyl chloride, is a colorless, volatile liquid with a pungent odor. It is a highly reactive chemical compound that is primarily used as a reagent in organic synthesis and as a solvent in chemical reactions. 1,1,1-Trichlorotrifluoroacetone is also used as a starting material in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity and potential for harmful health effects, including irritation to the eyes, skin, and respiratory system, as well as central nervous system depression, it is important to handle this chemical with caution and ensure proper safety measures are in place when working with it. Additionally, it is considered environmentally hazardous and should be handled and disposed of properly to prevent harm to the environment.

InChI:InChI=1/C8H5F5O/c1-2(14)3-4(9)6(11)8(13)7(12)5(3)10/h2,14H,1H3

Upstream product

• 79-53-8 chloropentafluoroacetone 
• 126266-75-9 3,3-dichloro-1,1,1-trifluoroacetone 
• 354-32-5 trifluoracetyl chloride 
• 3294-58-4 phenyl(bromodichloromethyl)mercury 

Downstream Products

• 76-05-1 trifluoroacetic acid 
• 89522-04-3 1-(4-fluorophenyl)-3-trifluoromethyl-5-methylthio-1,2,4-triazole 
• 89522-05-4 1-(4-chlorophenyl)-3-trifluoromethyl-5-methylthio-1,2,4-triazole 
• 89522-06-5 1-(3-chlorophenyl)-3-trifluoromethyl-5-methylthio-1,2,4-triazole 
• 89522-07-6 1-(3,4-dichlorophenyl)-3-trifluoromethyl-5-methylthio-1,2,4-triazole 
• 89522-03-2 1-phenyl-3-trifluoromethyl-5-methylthio-1,2,4-triazole 
• 421-50-1 1,1,1-trifluoro-2-propanone 
• 430-51-3 1-fluoro-2-propanone 
• 431-05-0 1,1-difluoroacetone 
• 67-64-1 acetone 
• 145938-92-7 1,1,1-Trichloro-3,3,3-trifluoro-2-phenyl-propan-2-ol 
• 67-66-3 chloroform 
• 350-09-4 N-trifluoroacetyl-L-phenylalanine 
• 2728-61-2 N-(trifluoroacetyl)-DL-phenylalanine 

Relevant articles and documents

Synthetic application of 3,3-dichloro-1, 1, 1-trifluoroacetone (DCTFA) and 3,3,3-trichloro-1, 1, 1-trifluoroacetone (TCTFA) for trifluorolactic acid derivatives

Synthetic application of 3,3-dichloro-1,1,1-trifluoroacetone (DCTFA) and 3,3,3-trichloro-1,1,1-trifluoroacetone (TCTFA) for industrially important trifluorolactic acid derivatives is described. Trifluorolactic acid was obtained by hydrolysis of DCTFA unde

Trifluoroacetylation of amino acids and peptides under neutral conditions.

-