75802-84-5 Usage
Description
4-chlorokynurenine (4-Cl-KYN) is a prodrug of 7-chlorokynurenic acid (7-Cl-KYNA), a potent and selective antagonist of the NMDA/glycine receptor. It is characterized by the presence of a chlorine atom at the 4-position of the kynurenine molecule, which allows it to readily penetrate the blood-brain barrier and provide antiexcitotoxic neuroprotection after systemic application.
Uses
Used in Pharmaceutical Industry:
4-chlorokynurenine is used as a prodrug for 7-chlorokynurenic acid, a potent and selective antagonist of the NMDA/glycine receptor, for the treatment of neurological disorders associated with excitotoxicity. Its ability to penetrate the blood-brain barrier makes it a promising candidate for the development of neuroprotective therapies.
Used in Neuroprotection:
4-chlorokynurenine is used as a neuroprotective agent to provide antiexcitotoxic protection against neuronal damage caused by excessive stimulation of the NMDA/glycine receptor. Its systemic application allows for the delivery of the active compound, 7-chlorokynurenic acid, to the brain, where it can modulate the receptor's activity and prevent excitotoxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 75802-84-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,8,0 and 2 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 75802-84:
(7*7)+(6*5)+(5*8)+(4*0)+(3*2)+(2*8)+(1*4)=145
145 % 10 = 5
So 75802-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H11ClN2O3/c11-5-1-2-6(7(12)3-5)9(14)4-8(13)10(15)16/h1-3,8H,4,12-13H2,(H,15,16)
