76106-70-2

Basic information

• Product Name: 3-hydroxybenzyl 2,4,4-trimethyl-6-oxo-cyclohex-1-enyl sulphone
• Synonyms: 3-hydroxybenzyl 2,4,4-trimethyl-6-oxo-cyclohex-1-enyl sulphone
• CAS NO: 76106-70-2
• Molecular Weight: 308.398
• Mol File: 76106-70-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-hydroxybenzyl 2,4,4-trimethyl-6-oxo-cyclohex-1-enyl sulphone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxybenzyl 2,4,4-trimethyl-6-oxo-cyclohex-1-enyl sulphone(76106-70-2)
• EPA Substance Registry System: 3-hydroxybenzyl 2,4,4-trimethyl-6-oxo-cyclohex-1-enyl sulphone(76106-70-2)

Safety Data

• Hazardous Substances Data: 76106-70-2(Hazardous Substances Data)

Upstream product

• 74597-04-9 m-hydroxybenzyl bromide 
• 76106-64-4 m-hydroxytoluene-α-thiol 
• 10276-21-8 isophorone oxide 
• 76106-65-5 2-(3-hydroxybenzylthio)-3,5,5-trimethylcyclohex-2-en-1-one 

Relevant articles and documents

Intramolecular Alkylation of Phenols. Part 4. Base-catalysed Cyclisation of Phenolic Enones. Scope and Limitations

The phenolic enones (4), (5), (8), (9), and (13) cyclise readily under acidic conditions.However, neither these nor the thio-substituted phenols (11a), (13a), (14a), and (15a) closed under basic conditions.Involvement of unfavourable equilibria is disproved.Comparison is made with related successful cyclisations of the saturated ketone (38) and aldehyde (39).Preliminary results suggest that strict stereo-electronic requirements are necessary for enone ring closure and that these conditions are not met in base-catalysed 5-Endo- and 6-Endo-Trigonal ring closures of the phenols of general type (2; n=0 and n=1).