76240-14-7 Usage
General Description
4-Pyrimidinecarboxylic acid, 2-methyl-, ethyl ester (9CI) is a chemical compound identified by the Chemical Abstracts Service (CAS) number 5185-15-1. As denoted by its name, it is derived from pyrimidine, a heterocyclic aromatic organic molecule similar to benzene. It is often used in the field of organic chemistry for research purposes, specifically in the synthesis of pyrimidine derivatives. Despite not being prominently featured in everyday applications, it has substantial value in the development of pharmaceuticals, where these derivatives are used in medications like antiviral and anticancer drugs, among others. Currently, there is limited information available about the compound's potential hazards or toxicity levels.
Check Digit Verification of cas no
The CAS Registry Mumber 76240-14-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,2,4 and 0 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 76240-14:
(7*7)+(6*6)+(5*2)+(4*4)+(3*0)+(2*1)+(1*4)=117
117 % 10 = 7
So 76240-14-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O2/c1-3-12-8(11)7-4-5-9-6(2)10-7/h4-5H,3H2,1-2H3
76240-14-7Relevant articles and documents
Reaction of β-alkoxyvinyl α-ketoesters with acyclic NCN binucleophiles – Scalable approach to novel functionalized pyrimidines
Stepaniuk, Oleksandr O.,Rudenko, Tymofii V.,Vashchenko, Bohdan V.,Matvienko, Vitalii O.,Kondratov, Ivan S.,Tolmachev, Andrey A.,Grygorenko, Oleksandr O.
, p. 3472 - 3478 (2019/05/17)
Two protocols for synthesis of series of low-molecular-weight di- and tri-substituted pyrimidines bearing a functional group at the 4th position, which rely on a base-mediated condensation of amidines or guanidines with β-alkoxyvinyl α-keto esters, have been developed. This approach allowed for multigram preparation of novel pyrimidine-4-carboxylates in 21–90% yield. The synthetic utility of these compounds was demonstrated by some standard functional group transformations providing promising building blocks for organic synthesis and drug discovery.
