766535-96-0 Usage
Derivative of indole
The compound is a derivative of indole, which is a common structural motif in organic chemistry.
Acetyl group attached
The nitrogen atom of the indole core is substituted with an acetyl group (-COCH3).
Use in synthesis
The compound is used as a building block in the synthesis of various pharmaceuticals and organic compounds.
Versatile reactivity
The compound's reactivity makes it valuable in chemical research and development.
Potential pharmacological activities
The compound is known for its potential pharmacological activities and is often studied for its therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 766535-96-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,6,5,3 and 5 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 766535-96:
(8*7)+(7*6)+(6*6)+(5*5)+(4*3)+(3*5)+(2*9)+(1*6)=210
210 % 10 = 0
So 766535-96-0 is a valid CAS Registry Number.
766535-96-0Relevant articles and documents
Organophotoredox assisted cyanation of bromoarenes: via silyl-radical-mediated bromine abstraction
Shah, Sk. Sheriff,Shee, Maniklal,Singh, N. D. Pradeep
supporting information, p. 4240 - 4243 (2020/04/22)
The insertion of a nitrile (-CN) group into arenes through the direct functionalization of the C(sp2)-Br bond is a challenging reaction. Herein, we report an organophotoredox method for the cyanation of aryl bromides using the organic photoredox catalyst 4CzIPN and tosyl cyanide (TsCN) as the nitrile source. A photogenerated silyl radical, via a single electron transfer (SET) mechanism, was employed to abstract bromine from aryl bromide to provide an aryl radical, which was concomitantly intercepted by TsCN to afford the aromatic nitrile. A range of substrates containing electron-donating and -withdrawing groups was demonstrated to undergo cyanation at room temperature in good yields.
